English
ezetimibe/simvastatin
Sign in to saveEzetimibe/simvastatin is a drug combination used for the treatment of dyslipidemia. It is a combination of ezetimibe (known as Zetia in the United States) and the statin drug simvastatin (known as Zocor in the US).
Research
338 papers- Ezetimibe/simvastatin.Expert opinion on drug safety · 2009
- Ezetimibe plus simvastatin for the treatment of hypercholesterolemia.Expert opinion on pharmacotherapy · 2015
- Ezetimibe/Simvastatin: a review of its use in the management of hypercholesterolemia.American journal of cardiovascular drugs : drugs, devices, and other interventions · 2004
- Benefit of Combination Ezetimibe/Simvastatin Among High-Risk Populations: Lessons from the IMPROVE-IT Trial.Current atherosclerosis reports · 2023
- Treatment of Alopecia Areata with Simvastatin/Ezetimibe.The journal of investigative dermatology. Symposium proceedings · 2018
via PubMed
~5 min read
Encyclopedic overview
10 sectionsContents
- Contraindications
- Side effects
- Interactions
- Pharmacology
- Clinical trials
- IMPROVE-IT trial
- ENHANCE trial data
- Subsequent debate and enquiries
- Advertising campaign
- References
Ezetimibe/simvastatin is a drug combination used for the treatment of dyslipidemia. It is a combination of ezetimibe (known as Zetia in the United States) and the statin drug simvastatin (known as Zocor in the US).
Ezetimibe reduces blood cholesterol by acting at the brush border of the small intestine and inhibiting the absorption of cholesterol, leading to a decrease in the delivery of intestinal cholesterol to the liver.
Excerpted from Wikipedia’s “ezetimibe/simvastatin” article, available under the CC BY-SA 4.0 licence.
Available in 7 languages
via Wikidata sitelinks · CC0