FABP3
Sign in to saveAlso known as FABP11, H-FABP, M-FABP, MDGI, O-FABP, Heart-type fatty acid binding protein, fatty acid binding protein 3
protein-coding gene in the species Homo sapiens
Gene data
FABP3- Name
- fatty acid binding protein 3
- Type
- protein-coding
- Position
- 31,359,583–31,376,850 (−)
- Aliases
- FABP11, H-FABP, M-FABP, MDGI, O-FABP
- Ensembl
- ENSG00000121769
- RefSeq RNA
- NM_001320996.2, NM_004102.5, XM_011541007.4, XM_054335131.1
- RefSeq protein
- NP_001307925.1, NP_004093.1, XP_011539309.1, XP_054191106.1
The intracellular fatty acid-binding proteins (FABPs) belongs to a multigene family. FABPs are divided into at least three distinct types, namely the hepatic-, intestinal- and cardiac-type. They form 14-15 kDa proteins and are thought to participate in the uptake, intracellular metabolism and/or transport of long-chain fatty acids. They may also be responsible in the modulation of cell growth and proliferation. Fatty acid-binding protein 3 gene contains four exons and its function is to arrest growth of mammary epithelial cells. This gene is a candidate tumor suppressor gene for human breast cancer. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Mar 2016].
Gene Ontology
Biological process
Molecular function
Pathways
via MyGene.info
Gene · Ensembl
fatty acid binding protein 3
- Symbol
- FABP3
- Biotype
- Protein coding
- Organism
- Homo sapiens
- Location
- 1:31,359,583-31,376,850
- Strand
- Reverse (−)
- Assembly
- GRCh38
via Ensembl · EMBL-EBI
Wikidata facts
- Instance of
- gene
- Image
- Protein FABP3 PDB 1g5w.png
Show 9 more facts
- HomoloGene ID
- 68379
- found in taxon
- Homo sapiens
- exact match
- identifiers.org/ncbigene/2170
- genomic end
- 31849697
- genomic start
- 31365253
- chromosome
- human chromosome 1
- cytogenetic location
- 1p35.2
- expressed in
- right coronary artery
- Commons category
- FABP3
via Wikidata · CC0