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famprofazone

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EntityQ5433492· pop 7· linked from 1,808 articles

famprofazone

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Famprofazone (Gewodin, Gewolen) is a nonsteroidal anti-inflammatory agent (NSAID) of the pyrazolone series which is available over-the-counter in some countries such as Taiwan. It has analgesic, anti-inflammatory, and antipyretic effects. Famprofazone has been known to produce methamphetamine as an active metabolite, with 15–20% of an oral dose being converted to it. As a result, famprofazone has occasionally been implicated in causing positives on drug tests for amphetamines.

Chemical data

Formula
C24H31N3O
Molecular weight
377.5 g/mol
IUPAC name
1-methyl-5-[[methyl(1-phenylpropan-2-yl)amino]methyl]-2-phenyl-4-propan-2-ylpyrazol-3-one
SMILES
CC(C)C1=C(N(N(C1=O)C2=CC=CC=C2)C)CN(C)C(C)CC3=CC=CC=C3
InChIKey
GNUXVOXXWGNPIV-UHFFFAOYSA-N
XLogP
5
Polar surface area
26.8 Ų
H-bond donors
0
H-bond acceptors
3
Formal charge
0

via PubChem

Drug data · ChEMBL

Max clinical phase
Phase 2
Molecule type
Small molecule

via ChEMBL · EBI

Wikidata facts

Mass
377.247
Show 2 more facts
chemical formula
C₂₄H₃₁N₃O
canonical SMILES
CC(C)C1=C(N(N(C1=O)C2=CC=CC=C2)C)CN(C)C(C)CC3=CC=CC=C3
Sources (2)

via Wikidata · CC0

~1 min read

Encyclopedic overview

2 sections
Contents
  • See also
  • References

{{Drugbox | IUPAC_name = 1-methyl-5-{[methyl(1-phenylpropan-2-yl)amino]methyl}-2-phenyl-4-(propan-2-yl)-1,2-dihydro-3H-pyrazol-3-one | image = Famprofazone.png | image_class = skin-invert-image

| tradename = | pregnancy_category = | legal_status = Rx-only | routes_of_administration = Oral

Excerpted from Wikipedia’s “famprofazone” article, available under the CC BY-SA 4.0 licence.

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