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GeneQ18039968· pop 6· linked from 2 articles

FCF1

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Also known as Bka, C14orf111, UTP24, CGI-35, FCF1 rRNA-processing protein, FCF1, rRNA-processing protein

rRNA-processing protein FCF1 homolog is a protein that in humans is encoded by the FCF1 gene.

In the Vinony graph

Within Vinony's link graph, FCF1 is referenced by 2 other articles, and connects out to PubMed, human chromosome 14 and Ensembl genome database project.

It is catalogued under the topic Genes on human chromosome 14.

Its subject is documented across 6 Wikipedia language editions.

Gene data

FCF1

Name: FCF1 rRNA-processing protein
Type: protein-coding
Position: 74,713,144–74,750,706 (+)
Aliases: Bka, C14orf111, CGI-35, UTP24
Ensembl: ENSG00000119616
RefSeq RNA: NM_001318508.2, NM_015962.5, XM_011536815.4, XM_011536816.4, XM_054376167.1
RefSeq protein: NP_001305437.1, NP_057046.1, XP_011535117.1, XP_011535118.1, XP_054232142.1

Enables RNA binding activity. Predicted to be involved in rRNA processing. Predicted to act upstream of or within endonucleolytic cleavage in 5'-ETS of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) and endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA). Predicted to be located in nucleoplasm. Predicted to be part of small-subunit processome. Predicted to be active in nucleolus. [provided by Alliance of Genome Resources, Apr 2022]

Gene Ontology

Biological process

endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)endonucleolytic cleavage to generate mature 5'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA)maturation of SSU-rRNA ribosomal small subunit biogenesis ribosomal small subunit biogenesis

Molecular function

RNA binding protein binding

Cellular component

nucleoplasm nucleolus nucleolus small-subunit processome small-subunit processome small-subunit processome small-subunit processome

Pathways

Ribosome biogenesis in eukaryotes - Homo sapiens (human)rRNA modification in the nucleus and cytosol Major pathway of rRNA processing in the nucleolus and cytosol rRNA processing rRNA processing rRNA processing in the nucleus and cytosol rRNA processing in the nucleus and cytosol Metabolism of RNA Metabolism of RNA

via MyGene.info

Gene · Ensembl

FCF1 rRNA-processing protein

Symbol: FCF1
Biotype: Protein coding
Organism: Homo sapiens
Location: 14:74,713,144-74,750,706
Strand: Forward (+)
Assembly: GRCh38

View on Ensembl →

via Ensembl · EMBL-EBI

Wikidata facts

Instance of: gene

Show 7 more facts

exact match: identifiers.org/ncbigene/51077
HomoloGene ID: 5706
chromosome: human chromosome 14
found in taxon: Homo sapiens
genomic start: 75179847
genomic end: 75203394
cytogenetic location: 14q24.3

Sources (4)

via Wikidata · CC0

~1 min read

Encyclopedic overview

2 sections

Contents

References
Further reading

rRNA-processing protein FCF1 homolog is a protein that in humans is encoded by the FCF1 gene.

==References==

Excerpted from Wikipedia’s “FCF1” article, available under the CC BY-SA 4.0 licence.

Available in 6 languages

via Wikidata sitelinks · CC0

Categories

Genes on human chromosome 14