FAF1
Sign in to saveAlso known as HFAF1s, UBXD12, UBXN3A, hFAF1, CGI-03, Fas associated factor 1
FAS-associated factor 1 is a protein that in humans is encoded by the FAF1 gene.
Gene data
FAF1- Name
- Fas associated factor 1
- Type
- protein-coding
- Aliases
- CGI-03, HFAF1s, UBXD12, UBXN3A, hFAF1
Interaction of Fas ligand (TNFSF6) with the FAS antigen (TNFRSF6) mediates programmed cell death, also called apoptosis, in a number of organ systems. The protein encoded by this gene binds to FAS antigen and can initiate apoptosis or enhance apoptosis initiated through FAS antigen. Initiation of apoptosis by the protein encoded by this gene requires a ubiquitin-like domain but not the FAS-binding domain. [provided by RefSeq, Jul 2008].
via MyGene.info
Gene · Ensembl
Fas associated factor 1
- Symbol
- FAF1
- Biotype
- Protein coding
- Organism
- Homo sapiens
- Location
- 1:50,437,028-50,960,288
- Strand
- Reverse (−)
- Assembly
- GRCh38
via Ensembl · EMBL-EBI
Wikidata facts
- Image
- Protein FAF1 PDB 1h8c.png
Show 5 more facts
- HomoloGene ID
- 5120
- exact match
- identifiers.org/ncbigene/11124
- genomic end
- 50960267
- genomic start
- 50905150
- cytogenetic location
- 1p32.3
via Wikidata · CC0
~1 min read
Article
2 sectionsContents
- References
- Further reading
FAS-associated factor 1 is a protein that in humans is encoded by the FAF1 gene.
Interaction of Fas ligand (TNFSF6) with the FAS antigen (TNFRSF6) mediates programmed cell death, also called apoptosis, in a number of organ systems. The protein encoded by this gene binds to FAS antigen and can initiate apoptosis or enhance apoptosis initiated through FAS antigen. Initiation of apoptosis by the protein encoded by this gene requires a ubiquitin-like domain but not the FAS-binding domain.