RSF1

Also known as HBXAP, RSF-1, XAP8, p325, remodeling and spacing factor 1

Remodeling and spacing factor 1 is a protein that in humans is encoded by the RSF1 gene.

In the Vinony graph

Within Vinony's link graph, RSF1 is referenced by 3 other articles, and connects out to PubMed, human chromosome 11 and Ensembl genome database project.

It is catalogued under the topic Genes on human chromosome 11.

Its subject is documented across 6 Wikipedia language editions.

Gene data

RSF1

Name: remodeling and spacing factor 1
Type: protein-coding
Position: 77,660,009–77,821,020 (−)
Aliases: HBXAP, RSF-1, XAP8, p325
Ensembl: ENSG00000048649
RefSeq RNA: NM_016578.4, XM_005274051.3, XM_017017923.2, XM_054369127.1, XM_054369128.1
RefSeq protein: NP_057662.3, XP_005274108.1, XP_016873412.1, XP_054225102.1, XP_054225103.1

This gene encodes a nuclear protein that interacts with hepatitis B virus X protein (HBX) and facilitates transcription of hepatitis B virus genes by the HBX transcription activator, suggesting a role for this interaction in the virus life cycle. This protein also interacts with SNF2H protein to form the RSF chromatin-remodeling complex, where the SNF2H subunit functions as the nucleosome-dependent ATPase, and this protein as the histone chaperone. [provided by RefSeq, Sep 2011].

Pathways

Cell Cycle Deposition of new CENPA-containing nucleosomes at the centromere Chromosome Maintenance Nucleosome assembly

via MyGene.info

Gene · Ensembl

remodeling and spacing factor 1

Symbol: RSF1
Biotype: Protein coding
Organism: Homo sapiens
Location: 11:77,660,009-77,821,020
Strand: Reverse (−)
Assembly: GRCh38

View on Ensembl →

via Ensembl · EMBL-EBI

Wikidata facts

Instance of: gene

Show 7 more facts

HomoloGene ID: 41142
found in taxon: Homo sapiens
exact match: identifiers.org/ncbigene/51773
genomic end: 77820869
genomic start: 77660009
chromosome: human chromosome 11
cytogenetic location: 11q14.1

Sources (3)

via Wikidata · CC0

~1 min read

Encyclopedic overview

2 sections

Contents

References
Further reading

Remodeling and spacing factor 1 is a protein that in humans is encoded by the RSF1 gene.

HBXAP is involved in transcription repression, transcription coactivation when associated with hepatitis B virus X protein (HBX), and chromatin remodeling and spacing when associated with SNF2H (MIM 603375).[supplied by OMIM]

Excerpted from Wikipedia’s “RSF1” article, available under the CC BY-SA 4.0 licence.