EDF1

Also known as EDF-1, MBF1, CFAP280, endothelial differentiation related factor 1

Endothelial differentiation-related factor 1 is a protein that in humans is encoded by the EDF1 gene.

Gene data

EDF1

Name: endothelial differentiation related factor 1
Type: protein-coding
Position: 136,862,115–136,866,312 (−)
Aliases: CFAP280, EDF-1, MBF1
Ensembl: ENSG00000107223
RefSeq RNA: NM_001281297.2, NM_001281298.2, NM_001281299.2, NM_003792.4, NM_153200.3
RefSeq protein: NP_001268226.1, NP_001268227.1, NP_001268228.1, NP_003783.1, NP_694880.1

This gene encodes a protein that may regulate endothelial cell differentiation, lipid metabolism, and hormone-induced cardiomyocyte hypertrophy. The encoded protein has also been found to act as a transcriptional coactivator by interconnecting the general transcription factor TATA element-binding protein (TBP) and gene-specific activators. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Jul 2013].