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فلکاینید

Structure via PubChem · Public domain (PubChem)

EntityQ421381· pop 19· linked from 378 articles

فلکاینید

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Also known as Tambocor®, Flecaine, N-(2-Piperidinylmethyl)-2,5-bis(2,2,2-trifluoroethoxy)benzamide, CCRIS 313, (+-)-flecainide, (+-)-Flecainide, Flecainide, Flecainida

Flecainide is a medication used to prevent and treat abnormally fast heart rates. This includes ventricular and supraventricular tachycardias. Its use is only recommended in those with dangerous arrhythmias or when significant symptoms cannot be managed with other treatments. Its use does not decrease a person's risk of death. It is taken by mouth or injection into a vein.

Chemical data

Formula
C17H20F6N2O3
Molecular weight
414.34 g/mol
IUPAC name
N-(piperidin-2-ylmethyl)-2,5-bis(2,2,2-trifluoroethoxy)benzamide
SMILES
C1CCNC(C1)CNC(=O)C2=C(C=CC(=C2)OCC(F)(F)F)OCC(F)(F)F
InChIKey
DJBNUMBKLMJRSA-UHFFFAOYSA-N
XLogP
3.8
Polar surface area
59.6 Ų
H-bond donors
2
H-bond acceptors
10
Formal charge
0

via PubChem

Drug data · ChEMBL

Max clinical phase
Approved
Molecule type
Small molecule
First approval
1985
Admin. routes
oral
Indications
atrial fibrillation, cardiac arrhythmia, Arrhythmogenic right ventricular dysplasia

via ChEMBL · EBI

Wikidata facts

Mass
414.138
Has use
medication
Show 7 more facts
chemical formula
C₁₇H₂₀F₆N₂O₃
significant drug interaction
darifenacin
canonical SMILES
C1CCNC(C1)CNC(=O)C2=C(C=CC(=C2)OCC(F)(F)F)OCC(F)(F)F
World Health Organisation international non-proprietary name
flecainide
medical condition treated
atrial fibrillation
Commons category
Flecainide
legal status (medicine)
boxed warning
Sources (6)

via Wikidata · CC0