Structure via PubChem · Public domain (PubChem)
furethidine
Sign in to saveFurethidine is a 4-phenylpiperidine derivative that is related to the clinically used opioid analgesic drug pethidine (meperidine), but with around 25x higher potency. According to another source, Furethidine is 500/30 = 16.7 x the potency of pethidine (table VII).
In the Vinony graph
Within Vinony's link graph, furethidine is referenced by 16 other articles, and connects out to (+)-catechin, butorphanol and Misuse of Drugs Act 1971.
Vinony files it under 4-Phenylpiperidines, Carboxylate esters and Drugs not assigned an ATC code.
Its subject is documented across 7 Wikipedia language editions.
Chemical data
- Formula
- C21H31NO4
- Molecular weight
- 361.5 g/mol
- IUPAC name
- ethyl 1-[2-(oxolan-2-ylmethoxy)ethyl]-4-phenylpiperidine-4-carboxylate
- SMILES
- CCOC(=O)C1(CCN(CC1)CCOCC2CCCO2)C3=CC=CC=C3
- InChIKey
- NNCOZXNZFLUYGG-UHFFFAOYSA-N
- XLogP
- 2.7
- Polar surface area
- 48 Ų
- H-bond donors
- 0
- H-bond acceptors
- 5
- Formal charge
- 0
via PubChem
Drug data · ChEMBL
- Max clinical phase
- Phase 2
- Molecule type
- Small molecule
via ChEMBL · EBI
Wikidata facts
- Subclass of
- chemical compound
- Mass
- 361.225308
Show 2 more facts
- chemical formula
- C₂₁H₃₁NO₄
- canonical SMILES
- CCOC(=O)C1(CCN(CC1)CCOCC2CCCO2)C3=CC=CC=C3
Sources (2)
via Wikidata · CC0
~1 min read
Encyclopedic overview
2 sectionsContents
- References
- External links
Furethidine is a 4-phenylpiperidine derivative that is related to the clinically used opioid analgesic drug pethidine (meperidine), but with around 25x higher potency. According to another source, Furethidine is 500/30 = 16.7 x the potency of pethidine (table VII).
Furethidine is not currently used in medicine and is a Class A/Schedule I drug which is controlled under UN drug conventions. It has similar effects to other opioid derivatives, such as analgesia, sedation, nausea and respiratory depression. In the United States it is a Schedule I Narcotic controlled substance with the ACSCN of 9626.
Excerpted from Wikipedia’s “furethidine” article, available under the CC BY-SA 4.0 licence.