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GeneQ18056158· pop 5· linked from 300 articles

Also known as CX25, bA136M9.1, connexin25, gap junction protein beta 7

Gap junction beta-7 protein (GJB7), also known as connexin-25 (Cx25), is a protein that in humans is encoded by the GJB7 gene.

Gene data

GJB7
Name
gap junction protein beta 7
Type
protein-coding
Position
87,282,980–87,329,278 (−)
Aliases
CX25, bA136M9.1, connexin25
RefSeq RNA
NM_198568.3
RefSeq protein
NP_940970.1

Connexins, such as GJB7, are involved in the formation of gap junctions, intercellular conduits that directly connect the cytoplasms of contacting cells. Each gap junction channel is formed by docking of 2 hemichannels, each of which contains 6 connexin subunits (Sohl et al., 2003 [PubMed 12881038]).[supplied by OMIM, Mar 2008].

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Gene · Ensembl

gap junction protein beta 7

Symbol
GJB7
Biotype
Protein coding
Organism
Homo sapiens
Location
6:87,282,980-87,329,278
Strand
Reverse (−)
Assembly
GRCh38
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via Ensembl · EMBL-EBI

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Encyclopedic overview

2 sections
Contents
  • Function
  • References

Gap junction beta-7 protein (GJB7), also known as connexin-25 (Cx25), is a protein that in humans is encoded by the GJB7 gene.

== Function == Connexins, such as GJB7, are involved in the formation of gap junctions, intercellular conduits that directly connect the cytoplasms of contacting cells. Each gap junction channel is formed by docking of 2 hemichannels, each of which contains 6 connexin subunits.

Excerpted from Wikipedia’s “GJB7” article, available under the CC BY-SA 4.0 licence.

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