گلی‌کوئیدون

Also known as ARDF-26, Glurenorm, Gliquidone

Gliquidone (INN, sold under the trade name Glurenorm) is an anti-diabetic medication in the sulfonylurea class. It is classified as a second-generation sulfonylurea. It is used in the treatment of diabetes mellitus type 2. It is marketed by the pharmaceutical company Boehringer Ingelheim (Germany).

In the Vinony graph

Vinony's link graph records 448 inbound references to گلی‌کوئیدون, and connects out to metformin, valproic acid and alogliptin.

Vinony files it under Benzenesulfonylureas, Cyclohexyl compounds and Drugs with non-standard legal status.

Vinony links it to 11 Wikipedia language editions.

Chemical data

Formula: C27H33N3O6S
Molecular weight: 527.6 g/mol
IUPAC name: 1-cyclohexyl-3-[4-[2-(7-methoxy-4,4-dimethyl-1,3-dioxoisoquinolin-2-yl)ethyl]phenyl]sulfonylurea

via PubChem

Drug data · ChEMBL

Max clinical phase: Phase 2
Molecule type: Small molecule
Indications: diabetes mellitus

via ChEMBL · EBI

Research

187 papers

Gliquidone.Acta crystallographica. Section E, Structure reports online · 2011
Gliquidone ameliorates hepatic insulin resistance in streptozotocin-induced diabetic Sur1(-/-) rats.European journal of pharmacology · 2021
Gliquidone contributes to improvement of type 2 diabetes mellitus management: a review of pharmacokinetic and clinical trial data.Drugs in R&D · 2006
Gliquidone Alleviates Diabetic Nephropathy by Inhibiting Notch/Snail Signaling Pathway.Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology · 2018
Inhibition of Cardiac Kv4.3/KChIP2 Channels by Sulfonylurea Drug Gliquidone.Molecular pharmacology · 2024

via PubMed

Wikidata facts

Subclass of: chemical compound
Mass: 527.209
Has use: medication

Show 5 more facts

chemical formula: C₂₇H₃₃N₃O₆S
World Health Organisation international non-proprietary name: gliquidone
canonical SMILES: CC1(C2=C(C=C(C=C2)OC)C(=O)N(C1=O)CCC3=CC=C(C=C3)S(=O)(=O)NC(=O)NC4CCCCC4)C
defined daily dose: 60
subject has role: anti-diabetic medication

Sources (3)

via Wikidata · CC0