glutethimide
Also known as Doriden®, 2-Ethyl-2-phenylglutarimide, Doriden
Glutethimide (brand names included Doriden, Elrodorm, and Noxyron) is a central nervous system (CNS) depressant drug of the piperidine chemical class, one of many non-barbiturate, "barbiturate-like" GABAergic medications exhibiting general calming, relaxing, or "tranquilizing" properties in addition to relieving anxiety and promoting sleep. As such, "nerve pills" or "sleeping pills" were common vernacular descriptions of these types of medications.
Chemical data
- Formula
- C13H15NO2
- Molecular weight
- 217.26 g/mol
- IUPAC name
- 3-ethyl-3-phenylpiperidine-2,6-dione
- SMILES
- CCC1(CCC(=O)NC1=O)C2=CC=CC=C2
- InChIKey
- JMBQKKAJIKAWKF-UHFFFAOYSA-N
- XLogP
- 1.9
- Polar surface area
- 46.2 Ų
- H-bond donors
- 1
- H-bond acceptors
- 2
- Formal charge
- 0
via PubChem
Research
2,279 papersArticle
8 sectionsContents
- History
- Chemical composition and synthesis
- Mechanism of action and uses
- Clinical research
- Legal status
- United States
- See also
- References
Glutethimide (brand names included Doriden, Elrodorm, and Noxyron) is a central nervous system (CNS) depressant drug of the piperidine chemical class, one of many non-barbiturate, "barbiturate-like" GABAergic medications exhibiting general calming, relaxing, or "tranquilizing" properties in addition to relieving anxiety and promoting sleep. As such, "nerve pills" or "sleeping pills" were common vernacular descriptions of these types of medications.
thumb | left| alt=Doriden