GZMM
Sign in to saveAlso known as LMET1, MET1, granzyme M
Granzyme M is a protein that in humans is encoded by the GZMM gene.
In the Vinony graph
Within Vinony's link graph, GZMM is referenced by 2 other articles, and connects out to PubMed, human chromosome 19 and Ensembl genome database project.
It is catalogued under the topic Genes on human chromosome 19.
Its subject is documented across 6 Wikipedia language editions.
Gene data
GZMM- Name
- granzyme M
- Type
- protein-coding
- Position
- 544,034–549,924 (+)
- Aliases
- LMET1, MET1
- Ensembl
- ENSG00000197540
- RefSeq RNA
- NM_001258351.2, NM_005317.4
- RefSeq protein
- NP_001245280.2, NP_005308.2
Human natural killer (NK) cells and activated lymphocytes express and store a distinct subset of neutral serine proteases together with proteoglycans and other immune effector molecules in large cytoplasmic granules. These serine proteases are collectively termed granzymes and include 4 distinct gene products: granzyme A, granzyme B, granzyme H, and the protein encoded by this gene, granzyme M. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Apr 2012].
Gene Ontology
Biological process
Molecular function
Cellular component
Pathways
via MyGene.info
Gene · Ensembl
granzyme M
- Symbol
- GZMM
- Biotype
- Protein coding
- Organism
- Homo sapiens
- Location
- 19:544,034-549,924
- Strand
- Forward (+)
- Assembly
- GRCh38
via Ensembl · EMBL-EBI
Wikidata facts
- Instance of
- gene
- Image
- Protein GZMM PDB 1LZP.png
Show 8 more facts
- HomoloGene ID
- 21099
- found in taxon
- Homo sapiens
- exact match
- identifiers.org/ncbigene/3004
- genomic end
- 549919
- genomic start
- 544034
- chromosome
- human chromosome 19
- cytogenetic location
- 19p13.3
- expressed in
- bone marrow
Sources (4)
via Wikidata · CC0
~1 min read
Encyclopedic overview
2 sectionsContents
- References
- Further reading
Granzyme M is a protein that in humans is encoded by the GZMM gene.
Human natural killer (NK) cells and activated lymphocytes express and store a distinct subset of neutral serine proteases together with proteoglycans and other immune effector molecules in large cytoplasmic granules. These serine proteases are collectively termed granzymes and include 4 distinct gene products: granzyme A, granzyme B, granzyme H, and Met-ase, also known as granzyme M.
Excerpted from Wikipedia’s “GZMM” article, available under the CC BY-SA 4.0 licence.