IFITM5

Also known as interferon induced transmembrane protein 5, BRIL, DSPA1, Hrmp1, OI5, fragilis4

protein-coding gene in the species Homo sapiens

In the Vinony graph

Within Vinony's link graph, IFITM5 is referenced by 6 other articles, and connects out to PubMed, human chromosome 11 and Ensembl genome database project.

It is catalogued under topics including Abnormalities of dermal fibrous and elastic tissue, Collagen disease and Genes on human chromosome 11.

Its subject is documented across 5 Wikipedia language editions.

Gene data

IFITM5

Name: interferon induced transmembrane protein 5
Type: protein-coding
Position: 298,200–299,533 (−)
Aliases: BRIL, DSPA1, Hrmp1, OI5, fragilis4
Ensembl: ENSG00000206013
RefSeq RNA: NM_001025295.3
RefSeq protein: NP_001020466.1

This gene encodes a membrane protein thought to play a role in bone mineralization. This gene is located on chromosome 11 in a cluster of related genes which are induced by interferon, however, this gene has not been shown to be interferon inducible. A similar gene, located in a gene cluster on mouse chromosome 7, is a member of the interferon-inducible fragilis gene family. The mouse gene encodes a transmembrane protein described as participating in germ cell competence. A mutation in the 5' UTR of this gene has been associated with osteogenesis imperfecta type V (PMID: 22863190, 22863195). [provided by RefSeq, Aug 2012].