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Structure via PubChem · Public domain (PubChem)
iodipamide
Sign in to saveAlso known as Cholografin, Adipiodone, Adipiodona, Adipiodonum, 3,3'-(adipoyldiimino)bis(2,4,6-triiodobenzoic acid)
Adipiodone (INN, or iodipamide; trade names Cholografin and Biligrafin) is a pharmaceutical drug used as a radiocontrast agent in X-ray imaging. It was introduced in the 1950s.
In the Vinony graph
Vinony's link graph records 62 inbound references to iodipamide, and connects out to radiocontrast agent, MRI contrast agent and microparticle.
It sits within the topics Anilides, Benzoic acids and Drugs with non-standard legal status.
Vinony links it to 6 Wikipedia language editions.
Chemical data
- Formula
- C20H14I6N2O6
- Molecular weight
- 1139.8 g/mol
- IUPAC name
- 3-[[6-(3-carboxy-2,4,6-triiodoanilino)-6-oxohexanoyl]amino]-2,4,6-triiodobenzoic acid
- SMILES
- C1=C(C(=C(C(=C1I)NC(=O)CCCCC(=O)NC2=C(C=C(C(=C2I)C(=O)O)I)I)I)C(=O)O)I
- InChIKey
- FFINMCNLQNTKLU-UHFFFAOYSA-N
- XLogP
- 5.5
- Polar surface area
- 133 Ų
- H-bond donors
- 4
- H-bond acceptors
- 6
- Formal charge
- 0
via PubChem
Drug data · ChEMBL
- Max clinical phase
- Approved
- Molecule type
- Small molecule
- First approval
- 1982
- Admin. routes
- parenteral, topical
via ChEMBL · EBI
Research
806 papers- Biliary excretion of iodipamide.Gastroenterology · 1975
- The choleretic effect of iodipamide.The Journal of clinical investigation · 1975
- Meglumine iodipamide (Cholografin) hepatotoxicity.Annals of internal medicine · 1977
- Saturation kinetics of iodipamide.Investigative radiology · 1977
- Iodipamide kinetics: capacity-limited biliary excretion with simultaneous pseudo-first-order renal excretion.Journal of pharmaceutical sciences · 1977
via PubMed
Wikidata facts
- Subclass of
- chemical compound
- Mass
- 1139.512
- Has use
- medication
Show 3 more facts
- canonical SMILES
- C1=C(C(=C(C(=C1I)NC(=O)CCCCC(=O)NC2=C(C=C(C(=C2I)C(=O)O)I)I)I)C(=O)O)I
- chemical formula
- C₂₀H₁₄I₆N₂O₆
- subject has role
- contrast agent
Sources (2)
via Wikidata · CC0
~2 min read
Encyclopedic overview
1 sectionsContents
- References
{{Drugbox | verifiedrevid = 477242817 | IUPAC_name = 3-{5-[(3-carboxy-2,4,6-triiodophenyl)carbamoyl]pentanamido}-2,4,6-triiodobenzoic acid | image = Adipiodone.png | image_class = skin-invert-image
| tradename = Cholografin, Biligrafin | Drugs.com = | pregnancy_AU = | pregnancy_US = | pregnancy_category = | legal_AU = | legal_CA = | legal_UK = | legal_US = | legal_status = Rx-only | routes_of_administration =
Excerpted from Wikipedia’s “iodipamide” article, available under the CC BY-SA 4.0 licence.