Skip to content
GeneQ18053062· pop 5· linked from 271 articles

Also known as CK-78, K5B, K78, Kb40, keratin 78

Keratin, type II cytoskeletal 78 is a protein that in humans is encoded by the KRT78 gene.

Gene data

KRT78
Name
keratin 78
Type
protein-coding
Aliases
CK-78, K5B, K78, Kb40

This gene is a member of the type II keratin gene family and encodes a protein with an intermediate filament domain. Keratins are the major structural proteins in epithelial cells, forming a cytoplasmic network of 10 to 12 nm wide intermediate filaments and creating a scaffold that gives cells the ability to withstand mechanical and non-mechanical stresses. The genes of the type II keratin family are located as a gene cluster at 12p13.13. Four pseudogenes of this gene family have been identified. [provided by RefSeq, Jul 2008].

via MyGene.info

Gene · Ensembl

keratin 78

Symbol
KRT78
Biotype
Protein coding
Organism
Homo sapiens
Location
12:52,837,804-52,849,092
Strand
Reverse (−)
Assembly
GRCh38
View on Ensembl →

via Ensembl · EMBL-EBI

Wikidata facts

Show 5 more facts
HomoloGene ID
65261
genomic end
53242876
genomic start
53231588
cytogenetic location
12q13.13
Sources (3)

via Wikidata · CC0

~1 min read

Article

2 sections
Contents
  • References
  • Further reading

Keratin, type II cytoskeletal 78 is a protein that in humans is encoded by the KRT78 gene.

This gene is a member of the type II keratin gene family and encodes a protein with an intermediate filament domain. Keratins are the major structural proteins in epithelial cells, forming a cytoplasmic network of 10 to 12 nm wide intermediate filaments and creating a scaffold that gives cells the ability to withstand mechanical and non-mechanical stresses. The genes of the type II keratin family are located as a gene cluster at 12p13.13. Four pseudogenes of this gene family have been identified.

Available in 5 languages

via Wikidata sitelinks · CC0

Connections

Categories