LDB2
Sign in to saveAlso known as CLIM1, LDB1, LDB-2, LIM domain binding 2
LIM domain-binding protein 2 is a protein that in humans is encoded by the LDB2 gene.
Gene data
LDB2- Name
- LIM domain binding 2
- Type
- protein-coding
- Position
- 16,501,534–16,898,924 (−)
- Aliases
- CLIM1, LDB-2, LDB1
- Ensembl
- ENSG00000169744
- RefSeq RNA
- NM_001130834.3, NM_001290.5, NM_001304434.2, NM_001304435.2, NR_130734.2
- RefSeq protein
- NP_001124306.1, NP_001281.1, NP_001291363.1, NP_001291364.1, XP_005248254.1
The protein encoded by this gene belongs to the LIM-domain binding family. Members of this family are characterized by a conserved nuclear localization sequence, an amino-terminal homodimerization domain and a carboxy-terminal LIM interaction domain. These proteins function as adapter molecules to allow assembly of transcriptional regulatory complexes. Genetic association studies suggest functions for this gene in rhegmatogenous retinal detachment and coronary artery disease. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2015].
Gene Ontology
Biological process
Molecular function
via MyGene.info
Gene · Ensembl
LIM domain binding 2
- Symbol
- LDB2
- Biotype
- Protein coding
- Organism
- Homo sapiens
- Location
- 4:16,501,534-16,898,961
- Strand
- Reverse (−)
- Assembly
- GRCh38
via Ensembl · EMBL-EBI
Wikidata facts
Show 5 more facts
- HomoloGene ID
- 989
- exact match
- identifiers.org/ncbigene/9079
- genomic end
- 16898678
- genomic start
- 16503164
- cytogenetic location
- 4p15.32
Sources (3)
via Wikidata · CC0
~1 min read
Article
3 sectionsContents
- See also
- References
- Further reading
LIM domain-binding protein 2 is a protein that in humans is encoded by the LDB2 gene.
== See also == LIM domain LIM domain-binding protein family