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levobetaxolol

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EntityQ6535758· pop 5· linked from 559 articles

levobetaxolol

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Also known as (-)-betaxolol, (S)-betaxolol, AL-1577A, Betaxon®, (S)-1-(isopropylamino)-3-[p-(cyclopropylmethoxyethyl)phenoxy]-2-propanol

Levobetaxolol is a drug used to lower the pressure in the eye in treating conditions such as glaucoma. It is marketed as a 0.25 or 0.5% ophthalmic solution of levobetaxolol hydrochloride under the trade name Betaxon. Levobetaxolol is a beta-adrenergic receptor inhibitor (beta blocker).

Chemical data

Formula
C18H29NO3
Molecular weight
307.4 g/mol
IUPAC name
(2S)-1-[4-[2-(cyclopropylmethoxy)ethyl]phenoxy]-3-(propan-2-ylamino)propan-2-ol
SMILES
CC(C)NC[C@@H](COC1=CC=C(C=C1)CCOCC2CC2)O
InChIKey
NWIUTZDMDHAVTP-KRWDZBQOSA-N
XLogP
2.8
Polar surface area
50.7 Ų
H-bond donors
2
H-bond acceptors
4
Formal charge
0

via PubChem

Drug data · ChEMBL

Max clinical phase
Approved
Molecule type
Small molecule
First approval
2000
Admin. routes
topical

via ChEMBL · EBI

Wikidata facts

Subclass of
betaxolol
Mass
307.214744
Has use
medication
Show 5 more facts
chemical formula
C₁₈H₂₉NO₃
canonical SMILES
CC(C)NCC(COC1=CC=C(C=C1)CCOCC2CC2)O
isomeric SMILES
CC(C)NC[C@@H](COC1=CC=C(C=C1)CCOCC2CC2)O
World Health Organisation international non-proprietary name
levobetaxolol
physically interacts with
adrenoceptor beta 2
Sources (2)

via Wikidata · CC0

~1 min read

Encyclopedic overview

5 sections
Contents
  • Indications
  • Effect
  • Contraindications and side effects
  • History
  • References

Levobetaxolol is a drug used to lower the pressure in the eye in treating conditions such as glaucoma. It is marketed as a 0.25 or 0.5% ophthalmic solution of levobetaxolol hydrochloride under the trade name Betaxon. Levobetaxolol is a beta-adrenergic receptor inhibitor (beta blocker).

== Indications == It is indicated for intraocular pressure reduction in patients with open-angle glaucoma or ocular hypertension.

Excerpted from Wikipedia’s “levobetaxolol” article, available under the CC BY-SA 4.0 licence.

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