LGALS2

Also known as HL14, galectin 2

Galectin-2 is a protein that in humans is encoded by the LGALS2 gene.

In the Vinony graph

Vinony's link graph records 3 inbound references to LGALS2, and connects out to PubMed, human chromosome 22 and Ensembl genome database project.

It is catalogued under the topic Genes on human chromosome 22.

Vinony links it to 6 Wikipedia language editions.

Gene data

LGALS2

Name: galectin 2
Type: protein-coding
Position: 37,570,246–37,582,616 (−)
Aliases: HL14
Ensembl: ENSG00000100079
RefSeq RNA: NM_006498.3
RefSeq protein: NP_006489.1

The protein encoded by this gene is a soluble beta-galactoside binding lectin. The encoded protein is found as a homodimer and can bind to lymphotoxin-alpha. A single nucleotide polymorphism in an intron of this gene can alter the transcriptional level of the protein, with a resultant increased risk of myocardial infarction. [provided by RefSeq, Jul 2008].

Gene Ontology

Biological process

T cell homeostasis positive regulation of apoptotic process positive regulation of inflammatory response cell-cell adhesion

Molecular function

protein binding galactoside binding carbohydrate binding carbohydrate binding

Cellular component

galectin complex

via MyGene.info

Gene · Ensembl

galectin 2

Symbol: LGALS2
Biotype: Protein coding
Organism: Homo sapiens
Location: 22:37,570,246-37,582,616
Strand: Reverse (−)
Assembly: GRCh38

View on Ensembl →

via Ensembl · EMBL-EBI

Wikidata facts

Instance of: gene
Image: Protein LGALS2 PDB 1hlc.png

Show 7 more facts

HomoloGene ID: 4741
found in taxon: Homo sapiens
exact match: identifiers.org/ncbigene/3957
genomic end: 37978623
genomic start: 37570248
chromosome: human chromosome 22
cytogenetic location: 22q13.1

Sources (4)

via Wikidata · CC0

~1 min read

Encyclopedic overview

2 sections

Contents

References
Further reading

Galectin-2 is a protein that in humans is encoded by the LGALS2 gene.

The protein encoded by this gene is a soluble beta-galactoside binding lectin. The encoded protein is found as a homodimer and can bind to Lymphotoxin alpha. A single nucleotide polymorphism in an intron of this gene can alter the transcriptional level of the protein, with a resultant increased risk of myocardial infarction.

Excerpted from Wikipedia’s “LGALS2” article, available under the CC BY-SA 4.0 licence.