LGALS2

Also known as HL14, galectin 2

Galectin-2 is a protein that in humans is encoded by the LGALS2 gene.

Gene data

LGALS2

Name: galectin 2
Type: protein-coding
Position: 37,570,246–37,582,616 (−)
Aliases: HL14
Ensembl: ENSG00000100079
RefSeq RNA: NM_006498.3
RefSeq protein: NP_006489.1

The protein encoded by this gene is a soluble beta-galactoside binding lectin. The encoded protein is found as a homodimer and can bind to lymphotoxin-alpha. A single nucleotide polymorphism in an intron of this gene can alter the transcriptional level of the protein, with a resultant increased risk of myocardial infarction. [provided by RefSeq, Jul 2008].

Gene Ontology

Biological process

T cell homeostasis positive regulation of apoptotic process positive regulation of inflammatory response cell-cell adhesion

Molecular function

protein binding galactoside binding carbohydrate binding carbohydrate binding

Cellular component

galectin complex

via MyGene.info

Gene · Ensembl

galectin 2

Symbol: LGALS2
Biotype: Protein coding
Organism: Homo sapiens
Location: 22:37,570,246-37,582,616
Strand: Reverse (−)
Assembly: GRCh38

View on Ensembl →

via Ensembl · EMBL-EBI

Wikidata facts

Image: Protein LGALS2 PDB 1hlc.png

Show 5 more facts

HomoloGene ID: 4741
exact match: identifiers.org/ncbigene/3957
genomic end: 37978623
genomic start: 37570248
cytogenetic location: 22q13.1

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Further reading

Galectin-2 is a protein that in humans is encoded by the LGALS2 gene.

The protein encoded by this gene is a soluble beta-galactoside binding lectin. The encoded protein is found as a homodimer and can bind to Lymphotoxin alpha. A single nucleotide polymorphism in an intron of this gene can alter the transcriptional level of the protein, with a resultant increased risk of myocardial infarction.