LGALS8
Sign in to saveAlso known as Gal-8, PCTA-1, PCTA1, Po66-CBP, galectin 8
Galectin-8 is a protein of the galectin family that in humans is encoded by the LGALS8 gene.
Gene data
LGALS8- Name
- galectin 8
- Type
- protein-coding
- Position
- 236,518,000–236,552,981 (+)
- Aliases
- Gal-8, PCTA-1, PCTA1, Po66-CBP
- Ensembl
- ENSG00000116977
- RefSeq RNA
- NM_006499.5, NM_201543.4, NM_201544.4, NM_201545.2, XM_011544188.4
- RefSeq protein
- NP_006490.3, NP_963837.1, NP_963838.1, NP_963839.1, XP_011542490.1
This gene encodes a member of the galectin family. Galectins are beta-galactoside-binding animal lectins with conserved carbohydrate recognition domains. The galectins have been implicated in many essential functions including development, differentiation, cell-cell adhesion, cell-matrix interaction, growth regulation, apoptosis, and RNA splicing. This gene is widely expressed in tumoral tissues and seems to be involved in integrin-like cell interactions. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Jul 2008].
Gene Ontology
Biological process
Molecular function
via MyGene.info
Gene · Ensembl
galectin 8
- Symbol
- LGALS8
- Biotype
- Protein coding
- Organism
- Homo sapiens
- Location
- 1:236,518,000-236,552,981
- Strand
- Forward (+)
- Assembly
- GRCh38
via Ensembl · EMBL-EBI
Wikidata facts
- Instance of
- gene
- Image
- Protein LGALS8 PDB 2YRO.png
Show 8 more facts
- HomoloGene ID
- 31386
- found in taxon
- Homo sapiens
- exact match
- identifiers.org/ncbigene/3964
- genomic end
- 236716281
- genomic start
- 236681300
- expressed in
- spleen
- chromosome
- human chromosome 1
- cytogenetic location
- 1q43
Sources (3)
via Wikidata · CC0
~3 min read
Encyclopedic overview
8 sectionsContents
- Function
- Galectin-8 levels
- Role in cancer
- Role in cellular defence
- Engineered galectin-8 assays
- Interactions
- References
- Further reading
Galectin-8 is a protein of the galectin family that in humans is encoded by the LGALS8 gene.
== Function ==
Excerpted from Wikipedia’s “LGALS8” article, available under the CC BY-SA 4.0 licence.