lisuride
Sign in to saveAlso known as (+)-lisuride, Dopergin®, lysuride, N'-((8alpha)-9,10-Didehydro-6-methylergolin-8-yl)-N,N-diethylurea, Lisuridum, Lisurid, Lisurida
Lisuride, sold under the brand name Dopergin among others, is a monoaminergic medication of the ergoline family which is used in the treatment of Parkinson's disease, migraine, and high prolactin levels. It is taken by mouth.
Research
1,030 papers- Are the LSD-analogs lisuride and ergotamine examples of non-hallucinogenic serotonin 5-HT2A receptor agonists?Journal of psychopharmacology (Oxford, England) · 2025
- Lisuride for levodopa-induced complications in Parkinson's disease.The Cochrane database of systematic reviews · 2000
- Lisuride in parkinsonism.Annals of neurology · 1981
- Lisuride, a dopamine receptor agonist with 5-HT2B receptor antagonist properties: absence of cardiac valvulopathy adverse drug reaction reports supports the concept of a crucial role for 5-HT2B receptor agonism in cardiac valvular fibrosis.Clinical neuropharmacology · 2006
- Lisuride versus bromocriptine for levodopa-induced complications in Parkinson's disease.The Cochrane database of systematic reviews · 2000
via PubMed
Wikidata facts
- Mass
- 338.210661
Show 6 more facts
- isomeric SMILES
- CCN(CC)C(=O)N[C@@H]1CN([C@@H]2CC3=CNC4=CC=CC(=C34)C2=C1)C
- canonical SMILES
- CCN(CC)C(=O)NC1CN(C2CC3=CNC4=CC=CC(=C34)C2=C1)C
- chemical formula
- C₂₀H₂₆N₄O
- defined daily dose
- 0.6
- World Health Organisation international non-proprietary name
- lisuride
- Commons category
- Lisuride
via Wikidata · CC0
~11 min read
Article
15 sectionsContents
- Medical uses
- Side effects
- Pharmacology
- Pharmacodynamics
- Pharmacokinetics
- Chemistry
- Analogues
- History
- Society and culture
- Generic names
- Brand names
- Availability
- Research
- See also
- References
Lisuride, sold under the brand name Dopergin among others, is a monoaminergic medication of the ergoline family which is used in the treatment of Parkinson's disease, migraine, and high prolactin levels. It is taken by mouth.
Side effects of lisuride include nausea and vomiting, dizziness, headache, fatigue or drowsiness, insomnia or sleep, gastrointestinal disturbances such as abdominal pain or diarrhea, nasal congestion or runny nose, and hypotension, and hallucinations or confusion (particularly at higher doses). Rarely, serious side effects such as cardiac or pulmonary fibrosis have been reported with long-term use, but they are extremely uncommon.