LYAR

Also known as ZC2HC2, ZLYAR, Ly1 antibody reactive

Cell growth-regulating nucleolar protein is a protein that in humans is encoded by the LYAR gene (Ly-1 antibody reactive clone).

Gene data

LYAR

Name: Ly1 antibody reactive
Type: protein-coding
Position: 4,267,572–4,290,196 (−)
Aliases: ZC2HC2, ZLYAR
Ensembl: ENSG00000145220
RefSeq RNA: NM_001145725.2, NM_017816.3, XM_011513505.2, XM_011513506.4, XM_054350460.1
RefSeq protein: NP_001139197.1, NP_060286.1, XP_011511807.1, XP_011511808.1, XP_054206435.1

Enables several functions, including DNA-binding transcription factor binding activity; identical protein binding activity; and transcription regulator inhibitor activity. Involved in several processes, including erythrocyte development; negative regulation of innate immune response; and regulation of transcription, DNA-templated. Located in nucleolus and nucleoplasm. [provided by Alliance of Genome Resources, Apr 2022]

Gene Ontology

Biological process

negative regulation of transcription by RNA polymerase II negative regulation of transcription by RNA polymerase II

Article

2 sections

Contents

References
Further reading

Cell growth-regulating nucleolar protein is a protein that in humans is encoded by the LYAR gene (Ly-1 antibody reactive clone).

LYAR contains a zinc finger motif and three copies of nuclear localization signals. LYAR is mainly localized to the nucleoli. LYAR is present at high levels in early embryos and preferentially in the liver fetal thymus.