LYAR

Also known as ZC2HC2, ZLYAR, Ly1 antibody reactive

Cell growth-regulating nucleolar protein is a protein that in humans is encoded by the LYAR gene (Ly-1 antibody reactive clone).

Gene data

LYAR

Name: Ly1 antibody reactive
Type: protein-coding
Position: 4,267,572–4,290,196 (−)
Aliases: ZC2HC2, ZLYAR
Ensembl: ENSG00000145220
RefSeq RNA: NM_001145725.2, NM_017816.3, XM_011513505.2, XM_011513506.4, XM_054350460.1
RefSeq protein: NP_001139197.1, NP_060286.1, XP_011511807.1, XP_011511808.1, XP_054206435.1

Enables several functions, including DNA-binding transcription factor binding activity; identical protein binding activity; and transcription regulator inhibitor activity. Involved in several processes, including erythrocyte development; negative regulation of innate immune response; and regulation of transcription, DNA-templated. Located in nucleolus and nucleoplasm. [provided by Alliance of Genome Resources, Apr 2022]

via MyGene.info

Gene · Ensembl

Ly1 antibody reactive

Symbol: LYAR
Biotype: Protein coding
Organism: Homo sapiens
Location: 4:4,267,572-4,290,196
Strand: Reverse (−)
Assembly: GRCh38

View on Ensembl →

via Ensembl · EMBL-EBI

Wikidata facts

Image: Protein LYAR PDB 1wjv.png

Show 5 more facts

HomoloGene ID: 41200
exact match: identifiers.org/ncbigene/55646
genomic end: 4290154
genomic start: 4269428
cytogenetic location: 4p16.3

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Cell growth-regulating nucleolar protein is a protein that in humans is encoded by the LYAR gene (Ly-1 antibody reactive clone).

LYAR contains a zinc finger motif and three copies of nuclear localization signals. LYAR is mainly localized to the nucleoli. LYAR is present at high levels in early embryos and preferentially in the liver fetal thymus.