Structure via PubChem · Public domain (PubChem)
mabuterol
Sign in to saveMabuterol is a selective β2 adrenoreceptor agonist.
In the Vinony graph
Within Vinony's link graph, mabuterol is referenced by 556 other articles, and connects out to propranolol, atenolol and adrenergic receptor.
It sits within the topics Aromatic amines, Chemical pages without DrugBank identifier and Chlorobenzene derivatives.
Its subject is documented across 6 Wikipedia language editions.
Chemical data
- Formula
- C13H18ClF3N2O
- Molecular weight
- 310.74 g/mol
- IUPAC name
- 1-[4-amino-3-chloro-5-(trifluoromethyl)phenyl]-2-(tert-butylamino)ethanol
- SMILES
- CC(C)(C)NCC(C1=CC(=C(C(=C1)Cl)N)C(F)(F)F)O
- InChIKey
- JSJCTEKTBOKRST-UHFFFAOYSA-N
- XLogP
- 2.5
- Polar surface area
- 58.3 Ų
- H-bond donors
- 3
- H-bond acceptors
- 6
- Formal charge
- 0
via PubChem
Drug data · ChEMBL
- Max clinical phase
- Phase 2
- Molecule type
- Small molecule
via ChEMBL · EBI
Research
78 papers- Development of mabuterol transdermal patch: Molecular mechanism study of ion-pair improving patch stability.International journal of pharmaceutics · 2023
- Toxicology of mabuterol.Arzneimittel-Forschung · 1984
- Inhibitory effect of mabuterol on proliferation of rat ASMCs induced by PDGF-BB via regulating [Ca(2+)]i and mitochondrial fission/fusion.Chemico-biological interactions · 2019
- Pharmacological studies of mabuterol, a new selective beta 2-stimulant. I: Bronchodilating effect.Arzneimittel-Forschung · 1984
- Beta-adrenoceptor blocking effects of a selective beta 2-agonist, mabuterol, on the isolated, blood-perfused right atrium of the dog.British journal of pharmacology · 1989
via PubMed
Wikidata facts
- Subclass of
- chemical compound
- Mass
- 310.106
Show 4 more facts
- chemical formula
- C₁₃H₁₈ClF₃N₂O
- canonical SMILES
- CC(C)(C)NCC(C1=CC(=C(C(=C1)Cl)N)C(F)(F)F)O
- subject has role
- bronchodilator
- Commons category
- Mabuterol
Sources (2)
via Wikidata · CC0
~2 min read
Encyclopedic overview
3 sectionsContents
- Synthesis
- See also
- References
Mabuterol is a selective β2 adrenoreceptor agonist.
==Synthesis== thumb|center|700px|class=skin-invert-image|Mabuterol synthesis
Excerpted from Wikipedia’s “mabuterol” article, available under the CC BY-SA 4.0 licence.
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