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methoxphenidine

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EntityQ15708281· pop 5· linked from 1,556 articles

methoxphenidine

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Methoxphenidine (methoxydiphenidine, 2-MeO-Diphenidine, MXP) is a dissociative of the diarylethylamine class that has been sold online as a designer drug. Methoxphenidine was first reported in a 1989 patent where it was tested as a treatment for neurotoxic injury. Shortly after the 2013 UK ban on arylcyclohexylamines methoxphenidine and the related compound diphenidine became available on the gray market, where it has been encountered as a powder and in tablet form. Though diphenidine possesses higher affinity for the NMDA receptor, anecdotal reports suggest methoxphenidine has greater oral po

In the Vinony graph

Vinony's link graph records 1,556 inbound references to methoxphenidine, and connects out to 2C-G, D-methamphetamine and benzylamine.

It sits within the topics 1,2-Diarylethylamines, 1-Piperidinyl compounds and 2-Methoxyphenyl compounds.

Vinony links it to 4 Wikipedia language editions.

Chemical data

Formula
C20H25NO
Molecular weight
295.4 g/mol
IUPAC name
1-[1-(2-methoxyphenyl)-2-phenylethyl]piperidine
SMILES
COC1=CC=CC=C1C(CC2=CC=CC=C2)N3CCCCC3
InChIKey
QXXCUXIRBHSITD-UHFFFAOYSA-N
XLogP
4.6
Polar surface area
12.5 Ų
H-bond donors
0
H-bond acceptors
2
Formal charge
0

via PubChem

Wikidata facts

Mass
295.194
Show 3 more facts
chemical formula
C₂₀H₂₅NO
canonical SMILES
COC1=CC=CC=C1C(CC2=CC=CC=C2)N3CCCCC3
Commons category
Methoxphenidine
Sources (2)

via Wikidata · CC0

~2 min read

Encyclopedic overview

4 sections
Contents
  • Side effects
  • Legal status
  • See also
  • References

Methoxphenidine (methoxydiphenidine, 2-MeO-Diphenidine, MXP) is a dissociative of the diarylethylamine class that has been sold online as a designer drug. Methoxphenidine was first reported in a 1989 patent where it was tested as a treatment for neurotoxic injury. Shortly after the 2013 UK ban on arylcyclohexylamines methoxphenidine and the related compound diphenidine became available on the gray market, where it has been encountered as a powder and in tablet form. Though diphenidine possesses higher affinity for the NMDA receptor, anecdotal reports suggest methoxphenidine has greater oral potency. Of the three isomeric anisyl-substituents methoxphenidine has affinity for the NMDA receptor that is higher than 4-MeO-diphenidine but lower than 3-MeO-diphenidine, a structure–activity relationship shared by the arylcyclohexylamines.

== Side effects ==

Excerpted from Wikipedia’s “methoxphenidine” article, available under the CC BY-SA 4.0 licence.

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