MICU1
Sign in to saveAlso known as CALC, CBARA1, EFHA3, MPXPS, mitochondrial calcium uptake 1, ara CALC
Calcium-binding atopy-related autoantigen 1 is a protein that in humans is encoded by the CBARA1 gene.
Gene data
MICU1- Name
- mitochondrial calcium uptake 1
- Type
- protein-coding
- Aliases
- CALC, CBARA1, EFHA3, MPXPS, ara CALC
This gene encodes an essential regulator of mitochondrial Ca2+ uptake under basal conditions. The encoded protein interacts with the mitochondrial calcium uniporter, a mitochondrial inner membrane Ca2+ channel, and is essential in preventing mitochondrial Ca2+ overload, which can cause excessive production of reactive oxygen species and cell stress. Alternatively spliced transcript variants encoding different isoforms have been described. [provided by RefSeq, Mar 2013].
via MyGene.info
Gene · Ensembl
mitochondrial calcium uptake 1
- Symbol
- MICU1
- Biotype
- Protein coding
- Organism
- Homo sapiens
- Location
- 10:72,355,297-72,626,134
- Strand
- Reverse (−)
- Assembly
- GRCh38
via Ensembl · EMBL-EBI
Wikidata facts
Show 5 more facts
- HomoloGene ID
- 4431
- exact match
- identifiers.org/ncbigene/10367
- genomic end
- 72626131
- genomic start
- 72367340
- cytogenetic location
- 10q22.1
via Wikidata · CC0
~1 min read
Article
4 sectionsContents
- Clinical
- References
- Further reading
- External links
Calcium-binding atopy-related autoantigen 1 is a protein that in humans is encoded by the CBARA1 gene.
==Clinical==