moexipril
Also known as RS-10085, SPM-925
Moexipril was an angiotensin converting enzyme inhibitor (ACE inhibitor) used for the treatment of hypertension and congestive heart failure. Moexipril can be administered alone or with other antihypertensives or diuretics.
Chemical data
- Formula
- C27H34N2O7
- Molecular weight
- 498.6 g/mol
- IUPAC name
- (3S)-2-[(2S)-2-[[(2S)-1-ethoxy-1-oxo-4-phenylbutan-2-yl]amino]propanoyl]-6,7-dimethoxy-3,4-dihydro-1H-isoquinoline-3-carboxylic acid
- SMILES
- CCOC(=O)[C@H](CCC1=CC=CC=C1)N[C@@H](C)C(=O)N2CC3=CC(=C(C=C3C[C@H]2C(=O)O)OC)OC
- InChIKey
- UWWDHYUMIORJTA-HSQYWUDLSA-N
- XLogP
- 1.2
- Polar surface area
- 114 Ų
- H-bond donors
- 2
- H-bond acceptors
- 8
- Formal charge
- 0
via PubChem
Research
124 papersArticle
5 sectionsContents
- Side effects
- Mechanism of action
- Pharmacology
- Synthesis
- References
Moexipril was an angiotensin converting enzyme inhibitor (ACE inhibitor) used for the treatment of hypertension and congestive heart failure. Moexipril can be administered alone or with other antihypertensives or diuretics.
It works by inhibiting the conversion of angiotensin I to angiotensin II.