MRPS5

Also known as MRP-S5, S5mt, mitochondrial ribosomal protein S5, 28S ribosomal protein S5, mitochondrial

protein-coding gene in the species Homo sapiens

Gene data

MRPS5

Name: mitochondrial ribosomal protein S5
Type: protein-coding
Aliases: MRP-S5, S5mt, uS5m

Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 28S subunit protein that belongs to the ribosomal protein S5P family. Pseudogenes corresponding to this gene are found on chromosomes 4q, 5q, and 18q. [provided by RefSeq, Jul 2008].

via MyGene.info