MRPS5

Also known as MRP-S5, S5mt, mitochondrial ribosomal protein S5, 28S ribosomal protein S5, mitochondrial

protein-coding gene in the species Homo sapiens

In the Vinony graph

Vinony's link graph records 206 inbound references to MRPS5, and connects out to mitochondrion, protein and ribosome.

Vinony files it under Genes on human chromosome 2 and Ribosomal proteins.

Vinony links it to 5 Wikipedia language editions.

Gene data

MRPS5

Name: mitochondrial ribosomal protein S5
Type: protein-coding
Position: 95,085,369–95,122,034 (−)
Aliases: MRP-S5, S5mt, uS5m
Ensembl: ENSG00000144029
RefSeq RNA: NM_001321995.2, NM_001321996.2, NM_001321997.2, NM_031902.5, NR_136152.2
RefSeq protein: NP_001308924.1, NP_001308925.1, NP_001308926.1, NP_114108.1

Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 28S subunit protein that belongs to the ribosomal protein S5P family. Pseudogenes corresponding to this gene are found on chromosomes 4q, 5q, and 18q. [provided by RefSeq, Jul 2008].