MRPS5
Sign in to saveAlso known as MRP-S5, S5mt, mitochondrial ribosomal protein S5, 28S ribosomal protein S5, mitochondrial
protein-coding gene in the species Homo sapiens
Gene data
MRPS5- Name
- mitochondrial ribosomal protein S5
- Type
- protein-coding
- Position
- 95,085,369–95,122,034 (−)
- Aliases
- MRP-S5, S5mt, uS5m
- Ensembl
- ENSG00000144029
- RefSeq RNA
- NM_001321995.2, NM_001321996.2, NM_001321997.2, NM_031902.5, NR_136152.2
- RefSeq protein
- NP_001308924.1, NP_001308925.1, NP_001308926.1, NP_114108.1
Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 28S subunit protein that belongs to the ribosomal protein S5P family. Pseudogenes corresponding to this gene are found on chromosomes 4q, 5q, and 18q. [provided by RefSeq, Jul 2008].
Gene Ontology
Biological process
Molecular function
Pathways
via MyGene.info
Gene · Ensembl
novel protein
- Biotype
- Protein coding
- Organism
- Homo sapiens
- Location
- 2:95,085,391-95,165,391
- Strand
- Reverse (−)
- Assembly
- GRCh38
via Ensembl · EMBL-EBI
Wikidata facts
Show 5 more facts
- HomoloGene ID
- 32726
- exact match
- identifiers.org/ncbigene/64969
- genomic end
- 95122027
- genomic start
- 95085369
- cytogenetic location
- 2q11.1
Sources (3)
via Wikidata · CC0