MTNR1B

Name

melatonin receptor 1B

Type

protein-coding

Position

92,969,651–92,985,066 (+)

Aliases

FGQTL2, MEL-1B-R, MT2

Ensembl

ENSG00000134640

RefSeq RNA

NM_005959.5, XM_011542839.3, XM_017017777.2, XM_054368848.1, XM_054368849.1

RefSeq protein

NP_005950.1, XP_011541141.1, XP_016873266.1, XP_054224823.1, XP_054224824.1

This gene encodes one of two high affinity forms of a receptor for melatonin, the primary hormone secreted by the pineal gland. This gene product is an integral membrane protein that is a G-protein coupled, 7-transmembrane receptor. It is found primarily in the retina and brain although this detection requires RT-PCR. It is thought to participate in light-dependent functions in the retina and may be involved in the neurobiological effects of melatonin. [provided by RefSeq, Jul 2008].