niclosamide
Also known as BAY-2353, Ex A Lint, Lintex, Nicloside, Niclocide, Yomesan
Niclosamide, sold under the brand name Niclocide among others, is an anthelmintic medication used to treat tapeworm infestations, including diphyllobothriasis, hymenolepiasis, and taeniasis. It is not effective against other worms such as flukes or roundworms. It is taken by mouth.
Chemical data
- Formula
- C13H8Cl2N2O4
- Molecular weight
- 327.12 g/mol
- IUPAC name
- 5-chloro-N-(2-chloro-4-nitrophenyl)-2-hydroxybenzamide
- SMILES
- C1=CC(=C(C=C1[N+](=O)[O-])Cl)NC(=O)C2=C(C=CC(=C2)Cl)O
- InChIKey
- RJMUSRYZPJIFPJ-UHFFFAOYSA-N
- XLogP
- 4
- Polar surface area
- 95.2 Ų
- H-bond donors
- 2
- H-bond acceptors
- 4
- Formal charge
- 0
via PubChem
Research
1,666 papers~3 min read
Article
7 sectionsContents
- Side effects
- Mechanism of action
- Use as a pesticide
- Medical research
- References
- Further reading
- External links
Niclosamide, sold under the brand name Niclocide among others, is an anthelmintic medication used to treat tapeworm infestations, including diphyllobothriasis, hymenolepiasis, and taeniasis. It is not effective against other worms such as flukes or roundworms. It is taken by mouth.
Side effects include nausea, vomiting, abdominal pain, and itchiness. It may be used during pregnancy. It works by blocking glucose uptake and oxidative phosphorylation by the worm.
Connections
Categories
AnthelminticsChlorobenzene derivativesDrugboxes which contain changes to verified fieldsDrugboxes which contain changes to watched fieldsDrugs with no legal statusECHA InfoCard ID from WikidataExperimental cancer drugsFungicidesNitrobenzene derivativesPesticidesPubChem ID (CID) same as WikidataSalicylanilides