niridazole
Sign in to saveAlso known as Ambilhar
Niridazole is a schistosomicide. It is used to treat schistosomiasis, the helmintic disease caused by certain flatworms (trematodes) from the genus Schistosoma (formerly Bilharzia). It is also known by its trade name Ambilhar. It is usually given as tablets.
Research
531 papers- Niridazole.British medical journal · 1966
- Anthelmintics.Drugs · 1977
- Carcinogenic effects of niridazole.Cancer letters · 1975
- Intestinal parasites.Gut · 1973
- 4-Keto niridazole: a major niridazole metabolite with central nervous system toxicity different than niridazole.The Journal of pharmacology and experimental therapeutics · 1984
via PubMed
Wikidata facts
- Subclass of
- chemical compound
- Mass
- 214.016
- Has use
- Amebicide
Show 4 more facts
- canonical SMILES
- C1CN(C(=O)N1)C2=NC=C(S2)[N+](=O)[O-]
- chemical formula
- C₆H₆N₄O₃S
- subject has role
- carcinogen
- Commons category
- Niridazole
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Encyclopedic overview
2 sectionsContents
- Mechanism of action
- References
Niridazole is a schistosomicide. It is used to treat schistosomiasis, the helmintic disease caused by certain flatworms (trematodes) from the genus Schistosoma (formerly Bilharzia). It is also known by its trade name Ambilhar. It is usually given as tablets.
Niridazole has central nervous system toxicity and can cause dangerous side effects, such as hallucinations. Also, it may cause allergic reactions in sensitive people. However, it is one of the most effective schistosomicide drugs.
Excerpted from Wikipedia’s “niridazole” article, available under the CC BY-SA 4.0 licence.
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