oxamniquine
Also known as UK-4271, Vansil, Mansil
Oxamniquine, sold under the brand name Vansil among others, is a medication used to treat schistosomiasis due to Schistosoma mansoni. Praziquantel, however, is often the preferred treatment. It is given by mouth and used as a single dose.
Key facts
- Drug.ATC_suffix
- BA02
- Drug.Verifiedfields
- changed
- Drug.verifiedrevid
- 462266611
- Drug.IUPAC_name
- (RS)-1,2,3,4-Tetrahydro-2-isopropylaminomethyl-7-nitro-6-quinolylmethanol
- Drug.image
- Oxamniquine enantiomers labelled.svg
- Drug.image_class
- skin-invert-image
- Drug.width
- 300
- Drug.image2
- Oxamniquine enantiomers ball-and-stick models from xtal.png
- Drug.image_class2
- bg-transparent
- Drug.width2
- 300
- Drug.chirality
- Racemic mixture
- Drug.tradename
- Vansil
~5 min read
Article
9 sectionsContents
- Medical uses
- Side effects
- Pharmacokinetics
- Mechanism of action
- History
- Brand names
- Stereochemistry
- References
- External links
Oxamniquine, sold under the brand name Vansil among others, is a medication used to treat schistosomiasis due to Schistosoma mansoni. Praziquantel, however, is often the preferred treatment. It is given by mouth and used as a single dose.
Common side effects include sleepiness, headache, nausea, diarrhea, and reddish urine. It is typically not recommended during pregnancy, if possible. Seizures may occur and therefore caution is recommended in people with epilepsy. It works by causing paralysis of the parasitic worms. It is in the anthelmintic family of medications.