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nintedanib
EntityQ15149723· pop 18· linked from 504 articles

nintedanib

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Also known as BIBF-1120, BIBF1120, Ofev®, Vargatef®, BIBF 1120, methyl (3Z)-3-[(4-{methyl[(4-methylpiperazin-1-yl)acetyl]amino}anilino)(phenyl)methylidene]-2-oxo-2,3-dihydro-1H-indole-6-carboxylate

Nintedanib, sold under the brand names Ofev and Vargatef, is an oral medication used for the treatment of idiopathic pulmonary fibrosis and along with other medications for some types of non-small-cell lung cancer.

Key facts

Drug.Verifiedfields
changed
Drug.verifiedrevid
428116657
Drug.image
Nintedanib.svg
Drug.image_class
skin-invert-image
Drug.alt
Nintedanib
Drug.caption
Nintedanib
Drug.tradename
Vargatef, Ofev
Drug.MedlinePlus
a615009
Drug.DailyMedID
Nintedanib
Drug.pregnancy_AU
D
Drug.routes_of_administration
By mouth
Drug.ATC_prefix
L01
Drug.ATC_suffix
EX09
Drug.legal_AU
S4
Drug.legal_CA
Rx-only
Drug.legal_US
Rx-only
Drug.legal_EU
Rx-only
Drug.legal_status
Rx-only

via Wikipedia infobox

~15 min read

Encyclopedic overview

20 sections
Contents
  • Medical uses
  • Idiopathic pulmonary fibrosis
  • Lung cancer
  • Contraindications
  • Adverse effects
  • Pharmacology
  • Mechanism of action
  • Pharmacokinetics
  • Interactions
  • Chemistry
  • History
  • Idiopathic pulmonary fibrosis
  • Lung cancer
  • Other interstitial lung diseases
  • Society and culture
  • Legal status
  • Brand names
  • Research
  • Breast cancer
  • References

{{Infobox drug | Verifiedfields = changed | verifiedrevid = 428116657 | image = Nintedanib.svg | image_class = skin-invert-image | width = | alt = Nintedanib | caption = Nintedanib

| pronounce = | tradename = Vargatef, Ofev | Drugs.com = | MedlinePlus = a615009 | DailyMedID = Nintedanib | pregnancy_AU = D | pregnancy_AU_comment = | pregnancy_category = | routes_of_administration = By mouth | class = | ATC_prefix = L01 | ATC_suffix = EX09 | ATC_supplemental =

Excerpted from Wikipedia’s “nintedanib” article, available under the CC BY-SA 4.0 licence.

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