nintedanib

Also known as BIBF-1120, BIBF1120, Ofev®, Vargatef®, BIBF 1120, methyl (3Z)-3-[(4-{methyl[(4-methylpiperazin-1-yl)acetyl]amino}anilino)(phenyl)methylidene]-2-oxo-2,3-dihydro-1H-indole-6-carboxylate

Nintedanib, sold under the brand names Ofev and Vargatef, is an oral medication used for the treatment of idiopathic pulmonary fibrosis and along with other medications for some types of non-small-cell lung cancer.

Key facts

Drug.Verifiedfields: changed
Drug.verifiedrevid: 428116657
Drug.image: Nintedanib.svg
Drug.image_class: skin-invert-image
Drug.alt: Nintedanib
Drug.caption: Nintedanib
Drug.tradename: Vargatef, Ofev
Drug.MedlinePlus: a615009
Drug.DailyMedID: Nintedanib
Drug.pregnancy_AU: D
Drug.routes_of_administration: By mouth
Drug.ATC_prefix: L01
Drug.ATC_suffix

~15 min read

Article

20 sections

Contents

Medical uses
Idiopathic pulmonary fibrosis
Lung cancer
Contraindications
Adverse effects
Pharmacology
Mechanism of action
Pharmacokinetics
Interactions
Chemistry
History
Idiopathic pulmonary fibrosis
Lung cancer
Other interstitial lung diseases
Society and culture
Legal status
Brand names
Research
Breast cancer
References

{{Infobox drug | Verifiedfields = changed | verifiedrevid = 428116657 | image = Nintedanib.svg | image_class = skin-invert-image | width = | alt = Nintedanib | caption = Nintedanib