NRP2
Sign in to saveAlso known as NP2, NPN2, PRO2714, VEGF165R2, neuropilin 2
protein-coding gene in the species Homo sapiens
In the Vinony graph
Within Vinony's link graph, NRP2 is referenced by 9 other articles, and connects out to PubMed, human chromosome 2 and Ensembl genome database project.
It is catalogued under the topic Genes on human chromosome 2.
Its subject is documented across 9 Wikipedia language editions.
Gene data
NRP2- Name
- neuropilin 2
- Type
- protein-coding
- Position
- 205,681,990–205,798,133 (+)
- Aliases
- NP2, NPN2, PRO2714, VEGF165R2
- Ensembl
- ENSG00000118257
- RefSeq RNA
- NM_003872.3, NM_018534.4, NM_201264.2, NM_201266.2, NM_201267.2
- RefSeq protein
- NP_003863.2, NP_061004.3, NP_957716.1, NP_957718.1, NP_957719.1
This gene encodes a member of the neuropilin family of receptor proteins. The encoded transmembrane protein binds to SEMA3C protein {sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C} and SEMA3F protein {sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3F}, and interacts with vascular endothelial growth factor (VEGF). This protein may play a role in cardiovascular development, axon guidance, and tumorigenesis. This protein has also been determined to act as a co-receptor for SARS-CoV-2 (which causes COVID-19) to infect host cells. [provided by RefSeq, Jul 2021].
Gene Ontology
Biological process
Molecular function
Pathways
via MyGene.info
Gene · Ensembl
neuropilin 2
- Symbol
- NRP2
- Biotype
- Protein coding
- Organism
- Homo sapiens
- Location
- 2:205,681,990-205,798,133
- Strand
- Forward (+)
- Assembly
- GRCh38
via Ensembl · EMBL-EBI
Wikidata facts
- Instance of
- gene
- Image
- Protein NRP2 PDB 2QQJ.png
Show 7 more facts
- found in taxon
- Homo sapiens
- exact match
- identifiers.org/ncbigene/8828
- HomoloGene ID
- 2875
- genomic end
- 206662857
- genomic start
- 206546714
- chromosome
- human chromosome 2
- cytogenetic location
- 2q33.3
Sources (4)
via Wikidata · CC0