NRP2

Also known as NP2, NPN2, PRO2714, VEGF165R2, neuropilin 2

protein-coding gene in the species Homo sapiens

Gene data

NRP2

Name: neuropilin 2
Type: protein-coding
Position: 205,681,990–205,798,133 (+)
Aliases: NP2, NPN2, PRO2714, VEGF165R2
Ensembl: ENSG00000118257
RefSeq RNA: NM_003872.3, NM_018534.4, NM_201264.2, NM_201266.2, NM_201267.2
RefSeq protein: NP_003863.2, NP_061004.3, NP_957716.1, NP_957718.1, NP_957719.1

This gene encodes a member of the neuropilin family of receptor proteins. The encoded transmembrane protein binds to SEMA3C protein {sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C} and SEMA3F protein {sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3F}, and interacts with vascular endothelial growth factor (VEGF). This protein may play a role in cardiovascular development, axon guidance, and tumorigenesis. This protein has also been determined to act as a co-receptor for SARS-CoV-2 (which causes COVID-19) to infect host cells. [provided by RefSeq, Jul 2021].