Also known as CDCA1, CT106, NUF2R, NUF2, NDC80 kinetochore complex component, NDC80 kinetochore complex component NUF2, NUF2 component of NDC80 kinetochore complex
Kinetochore protein Nuf2 is a protein that in humans is encoded by the NUF2 gene.
This gene encodes a protein that is highly similar to yeast Nuf2, a component of a conserved protein complex associated with the centromere. Yeast Nuf2 disappears from the centromere during meiotic prophase when centromeres lose their connection to the spindle pole body, and plays a regulatory role in chromosome segregation. The encoded protein is found to be associated with centromeres of mitotic HeLa cells, which suggests that this protein is a functional homolog of yeast Nuf2. Alternatively spliced transcript variants that encode the same protein have been described. [provided by RefSeq, Jul 2008].
Biological process
Kinetochore protein Nuf2 is a protein that in humans is encoded by the NUF2 gene.
This gene encodes a protein that is highly similar to yeast Nuf2, a component of a conserved protein complex associated with the centromere. Yeast Nuf2 disappears from the centromere during meiotic prophase when centromeres lose their connection to the spindle pole body, and plays a regulatory role in chromosome segregation.
Molecular function
via MyGene.info
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Discovered by embedding cosine similarity (sentence-transformers MiniLM, 384-dim).