NUF2
Sign in to saveAlso known as CDCA1, CT106, NUF2R, NUF2, NDC80 kinetochore complex component, NDC80 kinetochore complex component NUF2, NUF2 component of NDC80 kinetochore complex
Kinetochore protein Nuf2 is a protein that in humans is encoded by the NUF2 gene.
In the Vinony graph
Vinony's link graph records 5 inbound references to NUF2, and connects out to PubMed, human chromosome 1 and Ensembl genome database project.
It is catalogued under the topic Genes on human chromosome 1.
Vinony links it to 7 Wikipedia language editions.
Gene data
NUF2- Name
- NUF2 component of NDC80 kinetochore complex
- Type
- protein-coding
- Position
- 163,266,576–163,355,766 (+)
- Aliases
- CDCA1, CT106, NUF2R
- Ensembl
- ENSG00000143228
- RefSeq RNA
- NM_031423.4, NM_145697.3, XM_011510036.2, XM_024450112.2, XM_024450113.2
- RefSeq protein
- NP_113611.2, NP_663735.2, XP_011508338.1, XP_024305880.1, XP_024305881.1
This gene encodes a protein that is highly similar to yeast Nuf2, a component of a conserved protein complex associated with the centromere. Yeast Nuf2 disappears from the centromere during meiotic prophase when centromeres lose their connection to the spindle pole body, and plays a regulatory role in chromosome segregation. The encoded protein is found to be associated with centromeres of mitotic HeLa cells, which suggests that this protein is a functional homolog of yeast Nuf2. Alternatively spliced transcript variants that encode the same protein have been described. [provided by RefSeq, Jul 2008].
Gene Ontology
Biological process
Molecular function
Pathways
via MyGene.info
Gene · Ensembl
NUF2 component of NDC80 kinetochore complex
- Symbol
- NUF2
- Biotype
- Protein coding
- Organism
- Homo sapiens
- Location
- 1:163,266,576-163,355,766
- Strand
- Forward (+)
- Assembly
- GRCh38
via Ensembl · EMBL-EBI
Wikidata facts
- Instance of
- gene
- Image
- Protein NUF2 PDB 2VE7.png
Show 8 more facts
- HomoloGene ID
- 40205
- found in taxon
- Homo sapiens
- exact match
- identifiers.org/ncbigene/83540
- genomic end
- 163325554
- genomic start
- 163236366
- chromosome
- human chromosome 1
- cytogenetic location
- 1q23.3
- expressed in
- trabecular bone
Sources (4)
via Wikidata · CC0
~1 min read
Encyclopedic overview
2 sectionsContents
- References
- Further reading
Kinetochore protein Nuf2 is a protein that in humans is encoded by the NUF2 gene.
This gene encodes a protein that is highly similar to yeast Nuf2, a component of a conserved protein complex associated with the centromere. Yeast Nuf2 disappears from the centromere during meiotic prophase when centromeres lose their connection to the spindle pole body, and plays a regulatory role in chromosome segregation.
Excerpted from Wikipedia’s “NUF2” article, available under the CC BY-SA 4.0 licence.