KIF18A

Also known as MS-KIF18A, PPP1R99, kinesin family member 18A

Kinesin family member KIF18A is a human protein encoded by the KIF18A gene. It is part of the kinesin family of motor proteins.

Gene data

KIF18A

Name: kinesin family member 18A
Type: protein-coding
Position: 28,020,618–28,108,183 (−)
Aliases: MS-KIF18A, PPP1R99
Ensembl: ENSG00000121621
RefSeq RNA: NM_031217.4, XM_017018379.2, XM_017018380.2, XM_054370093.1, XM_054370094.1
RefSeq protein: NP_112494.3, XP_016873868.1, XP_016873869.1, XP_054226068.1, XP_054226069.1

KIF18A is a member of the kinesin superfamily of microtubule-associated molecular motors (see MIM 148760) that use hydrolysis of ATP to produce force and movement along microtubules (Luboshits and Benayahu, 2005 [PubMed 15878648]).[supplied by OMIM, Aug 2008].

Gene Ontology

Biological process

mitotic sister chromatid segregation mitotic cell cycle

~1 min read

Article

5 sections

Contents

Function
Therapeutic Target
References
Further reading
External links

Kinesin family member KIF18A is a human protein encoded by the KIF18A gene. It is part of the kinesin family of motor proteins.

== Function == KIF18A is a plus-end directed motor protein, and migrates to the plus ends of the spindle during early mitosis. It first accumulates there during prophase and metaphase, and is depleted during anaphase.