KIF18A

Also known as MS-KIF18A, PPP1R99, kinesin family member 18A

Kinesin family member KIF18A is a human protein encoded by the KIF18A gene. It is part of the kinesin family of motor proteins.

In the Vinony graph

Vinony's link graph records 270 inbound references to KIF18A, and connects out to hair keratin, PubMed and human chromosome 11.

It is catalogued under topics including Genes on human chromosome 11, Human proteins and Long stubs with short prose.

Vinony links it to 6 Wikipedia language editions.

Gene data

KIF18A

Name: kinesin family member 18A
Type: protein-coding
Position: 28,020,618–28,108,186 (−)
Aliases: MS-KIF18A, PPP1R99
Ensembl: ENSG00000121621
RefSeq RNA: NM_031217.4, XM_017018379.2, XM_017018380.2, XM_054370093.1, XM_054370094.1
RefSeq protein: NP_112494.3, XP_016873868.1, XP_016873869.1, XP_054226068.1, XP_054226069.1

KIF18A is a member of the kinesin superfamily of microtubule-associated molecular motors (see MIM 148760) that use hydrolysis of ATP to produce force and movement along microtubules (Luboshits and Benayahu, 2005 [PubMed 15878648]).[supplied by OMIM, Aug 2008].

Pathways

Hemostasis Hemostasis Adaptive Immune System Amplification of signal from the kinetochores Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal Signal Transduction Cell Cycle Immune System Signaling by Rho GTPases RHO GTPase Effectors

via MyGene.info

Gene · Ensembl

kinesin family member 18A

Symbol: KIF18A
Biotype: Protein coding
Organism: Homo sapiens
Location: 11:28,020,618-28,108,186
Strand: Reverse (−)
Assembly: GRCh38

View on Ensembl →

via Ensembl · EMBL-EBI

Wikidata facts

Instance of: gene
Image: KIF18A.png

Show 8 more facts

HomoloGene ID: 41820
found in taxon: Homo sapiens
exact match: identifiers.org/ncbigene/81930
genomic end: 28108156
genomic start: 28020619
chromosome: human chromosome 11
cytogenetic location: 11p14.1
expressed in: bone marrow

Sources (4)

via Wikidata · CC0

~1 min read

Encyclopedic overview

5 sections

Contents

Function
Therapeutic Target
References
Further reading
External links

Kinesin family member KIF18A is a human protein encoded by the KIF18A gene. It is part of the kinesin family of motor proteins.

== Function == KIF18A is a plus-end directed motor protein, and migrates to the plus ends of the spindle during early mitosis. It first accumulates there during prophase and metaphase, and is depleted during anaphase.

Excerpted from Wikipedia’s “KIF18A” article, available under the CC BY-SA 4.0 licence.