PARVB
Sign in to saveAlso known as CGI-56, parvin beta
Beta-parvin is a protein that in humans is encoded by the PARVB gene.
In the Vinony graph
Vinony's link graph records 8 inbound references to PARVB, and connects out to PubMed, human chromosome 22 and Ensembl genome database project.
It is catalogued under the topic Genes on human chromosome 22.
Vinony links it to 8 Wikipedia language editions.
Gene data
PARVB- Name
- parvin beta
- Type
- protein-coding
- Position
- 43,999,211–44,172,939 (+)
- Aliases
- CGI-56
- Ensembl
- ENSG00000188677
- RefSeq RNA
- NM_001003828.3, NM_001243385.2, NM_001243386.2, NM_013327.5, XM_017028792.3
- RefSeq protein
- NP_001003828.1, NP_001230314.1, NP_001230315.1, NP_037459.2, XP_016884281.1
This gene encodes a member of the parvin family of actin-binding proteins, which play a role in cytoskeleton organization and cell adhesion. These proteins are associated with focal contacts and contain calponin homology domains that bind to actin filaments. This family member binds to alphaPIX and alpha-actinin, and it can inhibit the activity of integrin-linked kinase. This protein also functions in tumor suppression. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, Aug 2011].
Gene Ontology
Biological process
Molecular function
Pathways
via MyGene.info
Gene · Ensembl
parvin beta
- Symbol
- PARVB
- Biotype
- Protein coding
- Organism
- Homo sapiens
- Location
- 22:43,999,211-44,172,939
- Strand
- Forward (+)
- Assembly
- GRCh38
via Ensembl · EMBL-EBI
Wikidata facts
- Instance of
- gene
Show 8 more facts
- HomoloGene ID
- 8342
- genetic association
- fatty liver disease
- found in taxon
- Homo sapiens
- exact match
- identifiers.org/ncbigene/29780
- genomic end
- 44172939
- genomic start
- 44395091
- chromosome
- human chromosome 22
- cytogenetic location
- 22q13.31
via Wikidata · CC0
~1 min read
Encyclopedic overview
2 sectionsContents
- References
- Further reading
Beta-parvin is a protein that in humans is encoded by the PARVB gene.
Members of the parvin family, including PARVB, PARVA and PARVG, are actin-binding proteins associated with focal contacts.[supplied by OMIM]
Excerpted from Wikipedia’s “PARVB” article, available under the CC BY-SA 4.0 licence.