PARVB
Sign in to saveAlso known as CGI-56, parvin beta
Beta-parvin is a protein that in humans is encoded by the PARVB gene.
Gene data
PARVB- Name
- parvin beta
- Type
- protein-coding
- Aliases
- CGI-56
This gene encodes a member of the parvin family of actin-binding proteins, which play a role in cytoskeleton organization and cell adhesion. These proteins are associated with focal contacts and contain calponin homology domains that bind to actin filaments. This family member binds to alphaPIX and alpha-actinin, and it can inhibit the activity of integrin-linked kinase. This protein also functions in tumor suppression. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, Aug 2011].
via MyGene.info
Gene · Ensembl
parvin beta
- Symbol
- PARVB
- Biotype
- Protein coding
- Organism
- Homo sapiens
- Location
- 22:43,999,211-44,172,939
- Strand
- Forward (+)
- Assembly
- GRCh38
via Ensembl · EMBL-EBI
Wikidata facts
Show 5 more facts
- HomoloGene ID
- 8342
- exact match
- identifiers.org/ncbigene/29780
- genomic end
- 44172939
- genomic start
- 44395091
- cytogenetic location
- 22q13.31
via Wikidata · CC0
~1 min read
Article
2 sectionsContents
- References
- Further reading
Beta-parvin is a protein that in humans is encoded by the PARVB gene.
Members of the parvin family, including PARVB, PARVA and PARVG, are actin-binding proteins associated with focal contacts.[supplied by OMIM]