PITPNB

Also known as PI-TP-beta, PtdInsTP, VIB1B, phosphatidylinositol transfer protein beta

Phosphatidylinositol transfer protein beta isoform is a protein that in humans is encoded by the PITPNB gene.

Gene data

PITPNB

Name: phosphatidylinositol transfer protein beta
Type: protein-coding
Position: 27,851,669–27,920,134 (−)
Aliases: PI-TP-beta, PtdInsTP, VIB1B
Ensembl: ENSG00000180957
RefSeq RNA: NM_001284277.2, NM_001284278.2, NM_012399.5, XM_011530052.3, XM_017028707.2
RefSeq protein: NP_001271206.1, NP_001271207.1, NP_036531.1, XP_011528354.1, XP_016884196.1

This gene encodes a cytoplasmic protein that catalyzes the transfer of phosphatidylinositol and phosphatidylcholine between membranes. This transfer activity is required for COPI complex-mediated retrograde transport from the Golgi apparatus to the endoplasmic reticulum. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, Sep 2013].

Pathways

Metabolism PI and PC transport between ER and Golgi membranes Glycerophospholipid biosynthesis PI Metabolism Phospholipid metabolism Metabolism of lipids

via MyGene.info

Gene · Ensembl

phosphatidylinositol transfer protein beta

Symbol: PITPNB
Biotype: Protein coding
Organism: Homo sapiens
Location: 22:27,851,423-27,920,134
Strand: Reverse (−)
Assembly: GRCh38

View on Ensembl →

via Ensembl · EMBL-EBI

Wikidata facts

Image: Protein PITPNB PDB 2a1l.png

Show 5 more facts

HomoloGene ID: 4533
exact match: identifiers.org/ncbigene/23760
genomic end: 28316122
genomic start: 28247657
cytogenetic location: 22q12.1

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Further reading

Phosphatidylinositol transfer protein beta isoform is a protein that in humans is encoded by the PITPNB gene.

The protein encoded by this gene is found in the cytoplasm, where it catalyzes the transfer of phosphatidylinositol and phosphatidylcholine between membranes.