PITPNB

Also known as PI-TP-beta, PtdInsTP, VIB1B, phosphatidylinositol transfer protein beta

Phosphatidylinositol transfer protein beta isoform is a protein that in humans is encoded by the PITPNB gene.

In the Vinony graph

Vinony's link graph records 2 inbound references to PITPNB, and connects out to PubMed, human chromosome 22 and Ensembl genome database project.

It is catalogued under the topic Genes on human chromosome 22.

Vinony links it to 6 Wikipedia language editions.

Gene data

PITPNB

Name: phosphatidylinositol transfer protein beta
Type: protein-coding
Position: 27,851,423–27,920,134 (−)
Aliases: PI-TP-beta, PtdInsTP, VIB1B
Ensembl: ENSG00000180957
RefSeq RNA: NM_001284277.2, NM_001284278.2, NM_012399.5, XM_011530052.3, XM_017028707.2
RefSeq protein: NP_001271206.1, NP_001271207.1, NP_036531.1, XP_011528354.1, XP_016884196.1

This gene encodes a cytoplasmic protein that catalyzes the transfer of phosphatidylinositol and phosphatidylcholine between membranes. This transfer activity is required for COPI complex-mediated retrograde transport from the Golgi apparatus to the endoplasmic reticulum. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, Sep 2013].

Pathways

Metabolism PI and PC transport between ER and Golgi membranes Glycerophospholipid biosynthesis PI Metabolism Phospholipid metabolism Metabolism of lipids

via MyGene.info

Gene · Ensembl

phosphatidylinositol transfer protein beta

Symbol: PITPNB
Biotype: Protein coding
Organism: Homo sapiens
Location: 22:27,851,423-27,920,134
Strand: Reverse (−)
Assembly: GRCh38

View on Ensembl →

via Ensembl · EMBL-EBI

Wikidata facts

Instance of: gene
Image: Protein PITPNB PDB 2a1l.png

Show 7 more facts

HomoloGene ID: 4533
found in taxon: Homo sapiens
exact match: identifiers.org/ncbigene/23760
genomic end: 28316122
genomic start: 28247657
chromosome: human chromosome 22
cytogenetic location: 22q12.1

Sources (3)

via Wikidata · CC0

~1 min read

Encyclopedic overview

2 sections

Contents

References
Further reading

Phosphatidylinositol transfer protein beta isoform is a protein that in humans is encoded by the PITPNB gene.

The protein encoded by this gene is found in the cytoplasm, where it catalyzes the transfer of phosphatidylinositol and phosphatidylcholine between membranes.

Excerpted from Wikipedia’s “PITPNB” article, available under the CC BY-SA 4.0 licence.