PLCB2
Sign in to saveAlso known as PLC-beta-2, phospholipase C beta 2
1-Phosphatidylinositol-4,5-bisphosphate phosphodiesterase beta-2 is an enzyme that in humans is encoded by the PLCB2 gene.
Gene data
PLCB2- Name
- phospholipase C beta 2
- Type
- protein-coding
- Aliases
- PLC-beta-2
The protein encoded by this gene is a phosphodiesterase that catalyzes the hydrolysis of phosphatidylinositol 4,5-bisphosphate to the second messengers inositol 1,4,5-trisphosphate (IP3) and diacylglycerol. The encoded protein is activated by G proteins and has been shown to be involved in the type 2 taste receptor signal transduction pathway. In addition, nuclear factor kappa B can regulate the transcription of this gene, whose protein product is also an important regulator of platelet responses. [provided by RefSeq, Jan 2017].
via MyGene.info
Gene · Ensembl
phospholipase C beta 2
- Symbol
- PLCB2
- Biotype
- Protein coding
- Organism
- Homo sapiens
- Location
- 15:40,278,176-40,307,965
- Strand
- Reverse (−)
- Assembly
- GRCh38
via Ensembl · EMBL-EBI
Wikidata facts
- Image
- Protein PLCB2 PDB 2fju.png
Show 5 more facts
- HomoloGene ID
- 20957
- exact match
- identifiers.org/ncbigene/5330
- genomic end
- 40600136
- genomic start
- 40570377
- cytogenetic location
- 15q15.1
Sources (4)
via Wikidata · CC0
~1 min read
Article
4 sectionsContents
- Function
- Interactions
- References
- Further reading
1-Phosphatidylinositol-4,5-bisphosphate phosphodiesterase beta-2 is an enzyme that in humans is encoded by the PLCB2 gene.
== Function ==