TAS2R16
Sign in to saveAlso known as T2R16, taste 2 receptor member 16, BGLPT
TAS2R16 (taste receptor, type 2, member 16) is a bitter taste receptor and one of the 25 TAS2Rs. TAS2Rs are receptors that belong to the G-protein-coupled receptors (GPCRs) family. These receptors detect various bitter substances found in nature as agonists, and get stimulated. TAS2R16 receptor is mainly expressed within taste buds present on the surface of the tongue and palate epithelium. TAS2R16 is activated by bitter β-glucopyranosides (such as salicin)
Gene data
TAS2R16- Name
- taste 2 receptor member 16
- Type
- protein-coding
- Position
- 122,994,704–122,995,700 (−)
- Aliases
- BGLPT, T2R16
- Ensembl
- ENSG00000128519
- RefSeq RNA
- NM_016945.3
- RefSeq protein
- NP_058641.1
This gene encodes a member of a family of candidate taste receptors that are members of the G protein-coupled receptor superfamily. These family members are specifically expressed by taste receptor cells of the tongue and palate epithelia. Each of these apparently intronless genes encodes a 7-transmembrane receptor protein, functioning as a bitter taste receptor. This gene is clustered with another 3 candidate taste receptor genes in chromosome 7 and is genetically linked to loci that influence bitter perception. [provided by RefSeq, Jul 2008].
Gene Ontology
Biological process
Molecular function
Pathways
via MyGene.info
Gene · Ensembl
taste 2 receptor member 16
- Symbol
- TAS2R16
- Biotype
- Protein coding
- Organism
- Homo sapiens
- Location
- 7:122,994,704-122,995,700
- Strand
- Reverse (−)
- Assembly
- GRCh38
via Ensembl · EMBL-EBI
~6 min read
Encyclopedic overview
12 sectionsContents
- Other names
- Gene
- Structure
- Function
- Ligands (from BitterDB)
- Single nucleotide polymorphisms
- Alcohol dependence
- Longevity
- See also
- References
- Further reading
- External links
TAS2R16 (taste receptor, type 2, member 16) is a bitter taste receptor and one of the 25 TAS2Rs. TAS2Rs are receptors that belong to the G-protein-coupled receptors (GPCRs) family. These receptors detect various bitter substances found in nature as agonists, and get stimulated. TAS2R16 receptor is mainly expressed within taste buds present on the surface of the tongue and palate epithelium. TAS2R16 is activated by bitter β-glucopyranosides (such as salicin)
== Other names == T2R16, Taste receptor 2 member 16, BGLPT.
Excerpted from Wikipedia’s “TAS2R16” article, available under the CC BY-SA 4.0 licence.