PCDH10
Sign in to saveAlso known as OL-PCDH, PCDH19, protocadherin 10
Protocadherin-10 is a protein that in humans is encoded by the PCDH10 gene.
In the Vinony graph
Vinony's link graph records 4 inbound references to PCDH10, and connects out to PubMed, human chromosome 4 and Ensembl genome database project.
It is catalogued under the topic Genes on human chromosome 4.
Vinony links it to 5 Wikipedia language editions.
Gene data
PCDH10- Name
- protocadherin 10
- Type
- protein-coding
- Position
- 133,149,285–133,208,606 (+)
- Aliases
- OL-PCDH
- Ensembl
- ENSG00000138650
- RefSeq RNA
- NM_020815.3, NM_032961.3, XM_011532150.2, XM_054350597.1
- RefSeq protein
- NP_065866.1, NP_116586.1, XP_011530452.1, XP_054206572.1
This gene belongs to the protocadherin gene family, a subfamily of the cadherin superfamily. This family member contains 6 extracellular cadherin domains, a transmembrane domain and a cytoplasmic tail differing from those of the classical cadherins. The encoded protein is a cadherin-related neuronal receptor thought to function in the establishment of specific cell-cell connections in the brain. This gene plays a role in inhibiting cancer cell motility and cell migration. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jan 2015].
Gene Ontology
Biological process
Molecular function
Cellular component
via MyGene.info
Gene · Ensembl
protocadherin 10
- Symbol
- PCDH10
- Biotype
- Protein coding
- Organism
- Homo sapiens
- Location
- 4:133,149,285-133,208,606
- Strand
- Forward (+)
- Assembly
- GRCh38
via Ensembl · EMBL-EBI
Wikidata facts
- Instance of
- gene
Show 8 more facts
- HomoloGene ID
- 74967
- found in taxon
- Homo sapiens
- exact match
- identifiers.org/ncbigene/57575
- genomic end
- 134129356
- genomic start
- 133149294
- chromosome
- human chromosome 4
- cytogenetic location
- 4q28.3
- expressed in
- putamen
Sources (3)
via Wikidata · CC0
~1 min read
Encyclopedic overview
2 sectionsContents
- References
- Further reading
Protocadherin-10 is a protein that in humans is encoded by the PCDH10 gene.
This gene belongs to the protocadherin gene family, a subfamily of the cadherin superfamily. The mRNA encodes a cadherin-related neuronal receptor thought to play a role in the establishment and function of specific cell-cell connections in the brain. This family member contains 6 extracellular cadherin domains, a transmembrane domain, and a cytoplasmic tail differing from those of the classical cadherins. Alternatively spliced transcripts encode isoforms with unique cytoplasmic domains.
Excerpted from Wikipedia’s “PCDH10” article, available under the CC BY-SA 4.0 licence.