PCDH1
Sign in to saveAlso known as PC42, PCDH42, protocadherin 1
Protocadherin-1 is a protein that in humans is encoded by the PCDH1 gene.
Gene data
PCDH1- Name
- protocadherin 1
- Type
- protein-coding
- Position
- 141,853,090–141,879,246 (−)
- Aliases
- PC42, PCDH42
- Ensembl
- ENSG00000156453
- RefSeq RNA
- NM_001278613.2, NM_001278615.1, NM_002587.5, NM_032420.5, XM_005268452.4
- RefSeq protein
- NP_001265542.1, NP_001265544.1, NP_002578.2, NP_115796.2, XP_005268509.2
This gene belongs to the protocadherin subfamily within the cadherin superfamily. The encoded protein is a membrane protein found at cell-cell boundaries. It is involved in neural cell adhesion, suggesting a possible role in neuronal development. The protein includes an extracelllular region, containing 7 cadherin-like domains, a transmembrane region and a C-terminal cytoplasmic region. Cells expressing the protein showed cell aggregation activity. Alternative splicing occurs in this gene. [provided by RefSeq, Jul 2008].
Gene Ontology
Biological process
Molecular function
via MyGene.info
Gene · Ensembl
protocadherin 1
- Symbol
- PCDH1
- Biotype
- Protein coding
- Organism
- Homo sapiens
- Location
- 5:141,853,090-141,879,246
- Strand
- Reverse (−)
- Assembly
- GRCh38
via Ensembl · EMBL-EBI
Wikidata facts
- Instance of
- gene
Show 7 more facts
- HomoloGene ID
- 12613
- found in taxon
- Homo sapiens
- exact match
- identifiers.org/ncbigene/5097
- genomic end
- 141258811
- genomic start
- 141853090
- chromosome
- human chromosome 5
- cytogenetic location
- 5q31.3
Sources (3)
via Wikidata · CC0
~1 min read
Encyclopedic overview
2 sectionsContents
- References
- Further reading
Protocadherin-1 is a protein that in humans is encoded by the PCDH1 gene.
This gene belongs to the protocadherin subfamily within the cadherin superfamily. The encoded protein is a membrane protein found at cell-cell boundaries. It is involved in neural cell adhesion, suggesting a possible role in neuronal development. The protein includes an extracellular region, containing 7 cadherin-like domains, a transmembrane region and a C-terminal cytoplasmic region. Cells expressing the protein showed cell aggregation activity. Alternative splicing occurs in this gene.
Excerpted from Wikipedia’s “PCDH1” article, available under the CC BY-SA 4.0 licence.