PRB1
Sign in to saveAlso known as PM, PMF, PMS, PRB1L, PRB1M, proline rich protein BstNI subfamily 1, proline rich protein BstNI subfamily 1 (gene/pseudogene)
Basic salivary proline-rich protein 1 is a protein that in humans is encoded by the PRB1 gene.
Gene data
PRB1- Name
- proline rich protein BstNI subfamily 1
- Type
- protein-coding
- Aliases
- PM, PMF, PMS, PRB1L, PRB1M
This gene encodes a member of the heterogeneous family of basic, proline-rich, human salivary glycoproteins. The encoded preproprotein undergoes proteolytic processing to generate one or more mature peptides before secretion from the parotid glands. Multiple alleles of this gene exhibiting variations in the length of the tandem repeats have been identified. The reference genome encodes the "Medium" allele. This gene is located in a cluster of closely related salivary proline-rich proteins on chromosome 12. Alternative splicing results in multiple transcript variants encoding different isoforms that may undergo similar proteolytic processing. [provided by RefSeq, Nov 2015]
via MyGene.info
Gene · Ensembl
proline rich protein BstNI subfamily 1
- Symbol
- PRB1
- Biotype
- Protein coding
- Organism
- Homo sapiens
- Location
- 12:11,351,823-11,355,591
- Strand
- Reverse (−)
- Assembly
- GRCh38
via Ensembl · EMBL-EBI
Wikidata facts
Show 4 more facts
- exact match
- identifiers.org/ncbigene/5542
- genomic start
- 11504757
- genomic end
- 11355591
- cytogenetic location
- 12p13.2
Sources (4)
via Wikidata · CC0
~1 min read
Article
2 sectionsContents
- References
- Further reading
Basic salivary proline-rich protein 1 is a protein that in humans is encoded by the PRB1 gene.
The protein encoded by this gene is a proline-rich salivary protein. This gene and five other genes that also encode salivary proline-rich proteins (PRPs), as well as a gene encoding a lacrimal gland PRP, form a PRP gene cluster in the chromosomal 12p13 region. Alternatively spliced transcript variants encoding distinct isoforms have been described.