English
prenalterol
Sign in to saveAlso known as CGP 7760B
Prenalterol, sold under the brand name Hyprenan, is a sympathomimetic agent and cardiac stimulant which acts as a β1-adrenergic receptor partial agonist and is used in the treatment of heart failure. It has selectivity for the β1-adrenergic receptor. Its partial agonist activity or intrinsic sympathomimetic activity is about 60%. It is said to have much greater impact on myocardial contractility than on heart rate. The drug has been marketed in Denmark, Norway, and Sweden.
Research
404 papers- Prenalterol--a new cardioselective inotropic agent.Journal of clinical and hospital pharmacy · 1982
- Electrophysiologic properties of prenalterol.International journal of cardiology · 1983
- The selectivity of xamoterol, prenalterol, and salbutamol as assessed by their effects in the presence and absence of ICI 118,551.Journal of cardiovascular pharmacology · 1988
- Electrophysiological studies with prenalterol.Acta medica Scandinavica. Supplementum · 1982
- Effect of prenalterol in asthmatic patients.European journal of clinical pharmacology · 1982
via PubMed
~3 min read
Encyclopedic overview
7 sectionsContents
- Chemistry
- Synthesis
- Stereospecific
- Racemic
- See also
- References
- Further reading
{{Drugbox | Verifiedfields = changed | verifiedrevid = 464213907 | IUPAC_name = 4-{[(2S)-2-hydroxy-3-(isopropylamino)propyl]oxy}phenol | image = Prenalterol.svg | image_class = skin-invert-image | width = 250px
| tradename = Hyprenan | pregnancy_category = | legal_status = Rx-only | routes_of_administration = Oral, IV
Excerpted from Wikipedia’s “prenalterol” article, available under the CC BY-SA 4.0 licence.