PREX1
Sign in to saveAlso known as P-REX1, phosphatidylinositol-3,4,5-trisphosphate dependent Rac exchange factor 1
Phosphatidylinositol 3,4,5-trisphosphate-dependent Rac exchanger 1 protein is a protein that in humans is encoded by the PREX1 gene.
Gene data
PREX1- Name
- phosphatidylinositol-3,4,5-trisphosphate dependent Rac exchange factor 1
- Type
- protein-coding
- Aliases
- P-REX1
The protein encoded by this gene acts as a guanine nucleotide exchange factor for the RHO family of small GTP-binding proteins (RACs). It has been shown to bind to and activate RAC1 by exchanging bound GDP for free GTP. The encoded protein, which is found mainly in the cytoplasm, is activated by phosphatidylinositol-3,4,5-trisphosphate and the beta-gamma subunits of heterotrimeric G proteins. [provided by RefSeq, Jul 2008].
via MyGene.info
Gene · Ensembl
phosphatidylinositol-3,4,5-trisphosphate dependent Rac exchange factor 1
- Symbol
- PREX1
- Biotype
- Protein coding
- Organism
- Homo sapiens
- Location
- 20:48,624,249-48,828,096
- Strand
- Reverse (−)
- Assembly
- GRCh38
via Ensembl · EMBL-EBI
Wikidata facts
Show 5 more facts
- exact match
- identifiers.org/ncbigene/57580
- HomoloGene ID
- 10821
- genomic start
- 47240790
- genomic end
- 48827999
- cytogenetic location
- 20q13.13
Sources (3)
via Wikidata · CC0
~1 min read
Article
4 sectionsContents
- Function
- Clinical significance
- References
- Further reading
Phosphatidylinositol 3,4,5-trisphosphate-dependent Rac exchanger 1 protein is a protein that in humans is encoded by the PREX1 gene.
== Function ==