PSG3

Also known as pregnancy specific beta-1-glycoprotein 3

Pregnancy-specific beta-1-glycoprotein 3 is a protein that in humans is encoded by the PSG3 gene.

In the Vinony graph

Within Vinony's link graph, PSG3 is referenced by 3 other articles, and connects out to PubMed, human chromosome 19 and Ensembl genome database project.

It is catalogued under the topic Genes on human chromosome 19.

Its subject is documented across 5 Wikipedia language editions.

Gene data

PSG3

Name: pregnancy specific beta-1-glycoprotein 3
Type: protein-coding
Position: 42,709,084–42,740,524 (−)
Ensembl: ENSG00000221826
RefSeq RNA: NM_021016.4, XM_011527126.3, XM_011527127.3, XM_054321487.1, XM_054321488.1
RefSeq protein: NP_066296.2, XP_011525428.1, XP_011525429.1, XP_054177462.1, XP_054177463.1

The human pregnancy-specific glycoproteins (PSGs) are a family of proteins that are synthesized in large amounts by placental trophoblasts and released into the maternal circulation during pregnancy. Molecular cloning and analysis of several PSG genes has indicated that the PSGs form a subgroup of the carcinoembryonic antigen (CEA) gene family, which belongs to the immunoglobulin superfamily of genes. Members of the CEA family consist of a single N domain, with structural similarity to the immunoglobulin variable domains, followed by a variable number of immunoglobulin constant-like A and/or B domains. Most PSGs have an arg-gly-asp (RGD) motif, which has been shown to function as an adhesion recognition signal for several integrins, in the N-terminal domain (summary by Teglund et al., 1994 [PubMed 7851896]). For additional general information about the PSG gene family, see PSG1 (MIM 176390).[supplied by OMIM, Oct 2009].