PIK3C2G
Sign in to saveAlso known as PI3K-C2-gamma, PI3K-C2GAMMA, phosphatidylinositol-4-phosphate 3-kinase catalytic subunit type 2 gamma
Phosphatidylinositol-4-phosphate 3-kinase C2 domain-containing gamma polypeptide is an enzyme that in humans is encoded by the PIK3C2G gene.
In the Vinony graph
Vinony's link graph records 6 inbound references to PIK3C2G, and connects out to PubMed, human chromosome 12 and Ensembl genome database project.
It is catalogued under the topic Genes on human chromosome 12.
Vinony links it to 5 Wikipedia language editions.
Gene data
PIK3C2G- Name
- phosphatidylinositol-4-phosphate 3-kinase catalytic subunit type 2 gamma
- Type
- protein-coding
- Position
- 18,242,947–18,648,416 (+)
- Aliases
- PI3K-C2-gamma, PI3K-C2GAMMA
- Ensembl
- ENSG00000139144
- RefSeq RNA
- NM_001288772.2, NM_001288774.2, NM_004570.6, XM_011520697.3, XM_011520701.3
- RefSeq protein
- NP_001275701.1, NP_001275703.1, NP_004561.3, XP_011518999.1, XP_011519003.1
The protein encoded by this gene belongs to the phosphoinositide 3-kinase (PI3K) family. PI3-kinases play roles in signaling pathways involved in cell proliferation, oncogenic transformation, cell survival, cell migration, and intracellular protein trafficking. This protein contains a lipid kinase catalytic domain as well as a C-terminal C2 domain, a characteristic of class II PI3-kinases. C2 domains act as calcium-dependent phospholipid binding motifs that mediate translocation of proteins to membranes, and may also mediate protein-protein interactions. This gene may play a role in several diseases, including type II diabetes. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2014].
Gene Ontology
Biological process
Molecular function
Cellular component
Pathways
via MyGene.info
Gene · Ensembl
phosphatidylinositol-4-phosphate 3-kinase catalytic subunit type 2 gamma
- Symbol
- PIK3C2G
- Biotype
- Protein coding
- Organism
- Homo sapiens
- Location
- 12:18,242,947-18,648,416
- Strand
- Forward (+)
- Assembly
- GRCh38
via Ensembl · EMBL-EBI
Wikidata facts
- Instance of
- gene
Show 8 more facts
- HomoloGene ID
- 3362
- found in taxon
- Homo sapiens
- exact match
- identifiers.org/ncbigene/5288
- genomic end
- 18801348
- genomic start
- 18242961
- chromosome
- human chromosome 12
- cytogenetic location
- 12p12.3
- expressed in
- seminal vesicula
Sources (3)
via Wikidata · CC0
~1 min read
Encyclopedic overview
2 sectionsContents
- References
- Further reading
Phosphatidylinositol-4-phosphate 3-kinase C2 domain-containing gamma polypeptide is an enzyme that in humans is encoded by the PIK3C2G gene.
The protein encoded by this gene belongs to the phosphoinositide 3-kinase (PI3K) family. PI3-kinases play roles in signaling pathways involved in cell proliferation, oncogenic transformation, cell survival, cell migration, and intracellular protein trafficking. This protein contains a lipid kinase catalytic domain as well as a C-terminal C2 domain, a characteristic of class II PI3-kinases. C2 domains act as calcium-dependent phospholipid binding motifs that mediate translocation of proteins to membranes, and may also mediate protein-protein interactions. The biological function of this gene has not yet been determined.
Excerpted from Wikipedia’s “PIK3C2G” article, available under the CC BY-SA 4.0 licence.