PSPH
Sign in to saveAlso known as PSP, PSPHD, phosphoserine phosphatase
Phosphoserine phosphatase is an enzyme that in humans is encoded by the PSPH gene.
In the Vinony graph
Within Vinony's link graph, PSPH is referenced by 6 other articles, and connects out to PubMed, Ensembl genome database project and enzyme.
It is catalogued under the topic Genes on human chromosome 7.
Its subject is documented across 5 Wikipedia language editions.
Gene data
PSPH- Name
- phosphoserine phosphatase
- Type
- protein-coding
- Position
- 56,010,119–56,051,609 (−)
- Aliases
- PSP, PSPHD
- Ensembl
- ENSG00000146733
- RefSeq RNA
- NM_001370503.1, NM_001370504.1, NM_001370505.1, NM_001370506.1, NM_001370507.1
- RefSeq protein
- NP_001357432.1, NP_001357433.1, NP_001357434.1, NP_001357435.1, NP_001357436.1
The protein encoded by this gene belongs to a subfamily of the phosphotransferases. This encoded enzyme is responsible for the third and last step in L-serine formation. It catalyzes magnesium-dependent hydrolysis of L-phosphoserine and is also involved in an exchange reaction between L-serine and L-phosphoserine. Deficiency of this protein is thought to be linked to Williams syndrome. [provided by RefSeq, Jul 2008].
Gene Ontology
Biological process
Molecular function
Pathways
via MyGene.info
Gene · Ensembl
phosphoserine phosphatase
- Symbol
- PSPH
- Biotype
- Protein coding
- Organism
- Homo sapiens
- Location
- 7:56,010,119-56,051,609
- Strand
- Reverse (−)
- Assembly
- GRCh38
via Ensembl · EMBL-EBI
Wikidata facts
- Instance of
- gene
- Image
- Protein PSPH PDB 1l8l.png
Show 8 more facts
- HomoloGene ID
- 31245
- exact match
- identifiers.org/ncbigene/5723
- found in taxon
- Homo sapiens
- genomic end
- 56119297
- genomic start
- 56078744
- chromosome
- human chromosome 7
- cytogenetic location
- 7p11.2
- expressed in
- caudate nucleus
via Wikidata · CC0
~1 min read
Encyclopedic overview
5 sectionsContents
- Function
- Clinical significance
- References
- Further reading
- External links
Phosphoserine phosphatase is an enzyme that in humans is encoded by the PSPH gene.
== Function ==
Excerpted from Wikipedia’s “PSPH” article, available under the CC BY-SA 4.0 licence.