Also known as HR21spB, REC8L1, Rec8p, REC8 meiotic recombination protein
Meiotic recombination protein REC8 homolog is a protein that in humans is encoded by the REC8 gene.
This gene encodes a member of the kleisin family of SMC (structural maintenance of chromosome) protein partners. The protein localizes to the axial elements of chromosomes during meiosis in both oocytes and spermatocytes. In the mouse, the homologous protein is a key component of the meiotic cohesion complex, which regulates sister chromatid cohesion and recombination between homologous chromosomes. Multiple alternatively spliced variants, encoding the same protein, have been found for this gene. [provided by RefSeq, Jul 2008].
via MyGene.info
Meiotic recombination protein REC8 homolog is a protein that in humans is encoded by the REC8 gene.
Rec8 is a meiosis-specific component of the cohesin complex that binds sister chromatids in preparation for the two divisions of meiosis. Rec8 is sequentially removed from sister chromatids. It is removed from the arms of chromosomes in the first division - separating homologous chromosomes from each other. However, Rec8 is maintained at centromeres so that sister chromatids are kept joined until anaphase of meiosis II, at which point removal of remaining cohesin leads to the separation of sister chromatids.
Discovered by embedding cosine similarity (sentence-transformers MiniLM, 384-dim).