ADAM8
Sign in to saveAlso known as CD156, CD156a, MS2, ADAM metallopeptidase domain 8
A Disintegrin and metalloproteinase domain-containing protein 8 is an enzyme that in humans is encoded by the ADAM8 gene.
Gene data
ADAM8- Name
- ADAM metallopeptidase domain 8
- Type
- protein-coding
- Position
- 133,262,416–133,276,909 (−)
- Aliases
- CD156, CD156a, MS2
- Ensembl
- ENSG00000151651
- RefSeq RNA
- NM_001109.5, NM_001164489.2, NM_001164490.2, XM_047424423.1, XM_047424424.1
- RefSeq protein
- NP_001100.3, NP_001157961.1, NP_001157962.1, XP_047280379.1, XP_047280380.1
This gene encodes a member of the ADAM (a disintegrin and metalloprotease domain) family. Members of this family are membrane-anchored proteins structurally related to snake venom disintegrins, and have been implicated in a variety of biological processes involving cell-cell and cell-matrix interactions, including fertilization, muscle development, and neurogenesis. The protein encoded by this gene may be involved in cell adhesion during neurodegeneration, and it is thought to be a target for allergic respiratory diseases, including asthma. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2009].
Gene Ontology
Biological process
Molecular function
Pathways
via MyGene.info
Gene · Ensembl
ADAM metallopeptidase domain 8
- Symbol
- ADAM8
- Biotype
- Protein coding
- Organism
- Homo sapiens
- Location
- 10:133,262,416-133,276,909
- Strand
- Reverse (−)
- Assembly
- GRCh38
via Ensembl · EMBL-EBI
~1 min read
Encyclopedic overview
5 sectionsContents
- Function
- See also
- References
- Further reading
- External links
A Disintegrin and metalloproteinase domain-containing protein 8 is an enzyme that in humans is encoded by the ADAM8 gene.
== Function ==
Excerpted from Wikipedia’s “ADAM8” article, available under the CC BY-SA 4.0 licence.