remikiren

Remikiren is a renin inhibitor under development for the treatment of hypertension (high blood pressure). It was first developed by Hoffmann–La Roche in 1996.

Research

68 papers

Discovery of remikiren as the first orally active renin inhibitor.Arzneimittel-Forschung · 1993
Remikiren (Ro 42-5892)--an orally active renin inhibitor in essential hypertension. Effects on blood pressure and the renin-angiotensin-aldosterone system.American journal of hypertension · 1996
Distribution of remikiren, a potent orally active inhibitor of human renin, in laboratory animals.Xenobiotica; the fate of foreign compounds in biological systems · 1996
Interaction of the renin inhibitor aliskiren with the SARS-CoV-2 main protease: a molecular docking study.Journal of biomolecular structure & dynamics · 2022
Excretion and metabolism of remikiren, a potent orally active inhibitor of primate renin.Xenobiotica; the fate of foreign compounds in biological systems · 1996

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References

Remikiren is a renin inhibitor under development for the treatment of hypertension (high blood pressure). It was first developed by Hoffmann–La Roche in 1996.

==References==